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Metal nanoparticles for biodetection

Publication ,  Journal Article
Oldenburg, SJ; Mock, JJ; Glass, J; Asenjo, A; Genick, C; Smith, DR; Schultz, DA; Schultz, S
Published in: Proceedings of SPIE - The International Society for Optical Engineering
December 1, 2002
Published version (DOI)

The large scattering cross section of plasmon resonant gold and silver nanoparticles functionalized with the appropriate ligand allows for sensitive and specific detection of nucleic acids and proteins. By varying the size, shape, and material morphology populations with a specific peak plasmon resonance can be prepared. By varying the order and length of plasmon resonant bar segment in a composite nanowire one can obtain a large number of particle populations. Distinct populations can be used for labels for multiplexing or as a platform for biological assays. An larger number of color populations can be obtained with composite nanowires that are fabricated with various lengths of silver, gold, or nickel segments. The order and length of the different plasmon resonance rod segments can be used to uniquely identify a rod population allowing for a large degree of multiplexing within a single sample.

Duke Scholars

David R. Smith
Author David R. Smith Electrical and Computer Engineering

Published In

Proceedings of SPIE - The International Society for Optical Engineering

DOI

10.1117/12.450805

ISSN

0277-786X

Publication Date

December 1, 2002

Volume

4810

Start / End Page

36 / 41

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware
  • 4006 Communications engineering
 

Citation

APA
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ICMJE
MLA
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Oldenburg, S. J., Mock, J. J., Glass, J., Asenjo, A., Genick, C., Smith, D. R., … Schultz, S. (2002). Metal nanoparticles for biodetection. Proceedings of SPIE - The International Society for Optical Engineering, 4810, 36–41. https://doi.org/10.1117/12.450805
Oldenburg, S. J., J. J. Mock, J. Glass, A. Asenjo, C. Genick, D. R. Smith, D. A. Schultz, and S. Schultz. “Metal nanoparticles for biodetection.” Proceedings of SPIE - The International Society for Optical Engineering 4810 (December 1, 2002): 36–41. https://doi.org/10.1117/12.450805.
Oldenburg SJ, Mock JJ, Glass J, Asenjo A, Genick C, Smith DR, et al. Metal nanoparticles for biodetection. Proceedings of SPIE - The International Society for Optical Engineering. 2002 Dec 1;4810:36–41.
Oldenburg, S. J., et al. “Metal nanoparticles for biodetection.” Proceedings of SPIE - The International Society for Optical Engineering, vol. 4810, Dec. 2002, pp. 36–41. Scopus, doi:10.1117/12.450805.
Oldenburg SJ, Mock JJ, Glass J, Asenjo A, Genick C, Smith DR, Schultz DA, Schultz S. Metal nanoparticles for biodetection. Proceedings of SPIE - The International Society for Optical Engineering. 2002 Dec 1;4810:36–41.

Published In

Proceedings of SPIE - The International Society for Optical Engineering

DOI

10.1117/12.450805

ISSN

0277-786X

Publication Date

December 1, 2002

Volume

4810

Start / End Page

36 / 41

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware
  • 4006 Communications engineering