Inflammation and herpes simplex virus: release of a chemotaxis-generating factor from infected cells.
Publication
, Journal Article
Brier, AM; Snyderman, R; Mergenhagen, SE; Notkins, AL
Published in: Science
December 4, 1970
Infection of primary rabbit kidney cells with herpes simplex virus leads to the release of a cell factor or factors that upon incubation with serum results in the cleavage of the fifth component, C5, of complement. The product of this cleavage, C5a, is chemotactic for polymorphonuclear leukocytes and could be responsible for the accumulation of these cells at the site of herpetic lesions.
Duke Scholars
Published In
Science
DOI
ISSN
0036-8075
Publication Date
December 4, 1970
Volume
170
Issue
3962
Start / End Page
1104 / 1106
Location
United States
Related Subject Headings
- Virus Cultivation
- Simplexvirus
- Rabbits
- Leukocytes
- Inflammation
- Guinea Pigs
- General Science & Technology
- Culture Techniques
- Culture Media
- Complement System Proteins
Citation
APA
Chicago
ICMJE
MLA
NLM
Brier, A. M., Snyderman, R., Mergenhagen, S. E., & Notkins, A. L. (1970). Inflammation and herpes simplex virus: release of a chemotaxis-generating factor from infected cells. Science, 170(3962), 1104–1106. https://doi.org/10.1126/science.170.3962.1104
Brier, A. M., R. Snyderman, S. E. Mergenhagen, and A. L. Notkins. “Inflammation and herpes simplex virus: release of a chemotaxis-generating factor from infected cells.” Science 170, no. 3962 (December 4, 1970): 1104–6. https://doi.org/10.1126/science.170.3962.1104.
Brier AM, Snyderman R, Mergenhagen SE, Notkins AL. Inflammation and herpes simplex virus: release of a chemotaxis-generating factor from infected cells. Science. 1970 Dec 4;170(3962):1104–6.
Brier, A. M., et al. “Inflammation and herpes simplex virus: release of a chemotaxis-generating factor from infected cells.” Science, vol. 170, no. 3962, Dec. 1970, pp. 1104–06. Pubmed, doi:10.1126/science.170.3962.1104.
Brier AM, Snyderman R, Mergenhagen SE, Notkins AL. Inflammation and herpes simplex virus: release of a chemotaxis-generating factor from infected cells. Science. 1970 Dec 4;170(3962):1104–1106.
Published In
Science
DOI
ISSN
0036-8075
Publication Date
December 4, 1970
Volume
170
Issue
3962
Start / End Page
1104 / 1106
Location
United States
Related Subject Headings
- Virus Cultivation
- Simplexvirus
- Rabbits
- Leukocytes
- Inflammation
- Guinea Pigs
- General Science & Technology
- Culture Techniques
- Culture Media
- Complement System Proteins