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Integrated circuit microchip system with multiplex capillary electrophoresis module for DNA analysis

Publication ,  Journal Article
Song, JM; Mobley, J; Vo-Dinh, T
Published in: Analytica Chimica Acta
August 27, 2002

In this paper, we describe the use of an integrated circuit (IC) microchip system as a detector in multiplex capillary electrophoresis (CE). This combination of multiplex capillary gel electrophoresis and the IC microchip technology represents a novel approach to DNA analysis on the microchip platform. Separation of DNA ladders using a multiplex CE microsystem of four capillaries was monitored simultaneously using the IC microchip system. The IC microchip-CE system has advantages such as low cost, rapid analysis, compactness, and multiplex capability, and has great potential as an alternative system to conventional capillary array gel electrophoresis systems based on charge-coupled device (CCD) detection. © 2002 Elsevier Science B.V. All rights reserved.

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Published In

Analytica Chimica Acta

DOI

ISSN

0003-2670

Publication Date

August 27, 2002

Volume

466

Issue

2

Start / End Page

187 / 192

Related Subject Headings

  • Analytical Chemistry
  • 4018 Nanotechnology
  • 4004 Chemical engineering
  • 3401 Analytical chemistry
  • 0399 Other Chemical Sciences
  • 0301 Analytical Chemistry
 

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Song, J. M., Mobley, J., & Vo-Dinh, T. (2002). Integrated circuit microchip system with multiplex capillary electrophoresis module for DNA analysis. Analytica Chimica Acta, 466(2), 187–192. https://doi.org/10.1016/S0003-2670(02)00552-4
Song, J. M., J. Mobley, and T. Vo-Dinh. “Integrated circuit microchip system with multiplex capillary electrophoresis module for DNA analysis.” Analytica Chimica Acta 466, no. 2 (August 27, 2002): 187–92. https://doi.org/10.1016/S0003-2670(02)00552-4.
Song JM, Mobley J, Vo-Dinh T. Integrated circuit microchip system with multiplex capillary electrophoresis module for DNA analysis. Analytica Chimica Acta. 2002 Aug 27;466(2):187–92.
Song, J. M., et al. “Integrated circuit microchip system with multiplex capillary electrophoresis module for DNA analysis.” Analytica Chimica Acta, vol. 466, no. 2, Aug. 2002, pp. 187–92. Scopus, doi:10.1016/S0003-2670(02)00552-4.
Song JM, Mobley J, Vo-Dinh T. Integrated circuit microchip system with multiplex capillary electrophoresis module for DNA analysis. Analytica Chimica Acta. 2002 Aug 27;466(2):187–192.
Journal cover image

Published In

Analytica Chimica Acta

DOI

ISSN

0003-2670

Publication Date

August 27, 2002

Volume

466

Issue

2

Start / End Page

187 / 192

Related Subject Headings

  • Analytical Chemistry
  • 4018 Nanotechnology
  • 4004 Chemical engineering
  • 3401 Analytical chemistry
  • 0399 Other Chemical Sciences
  • 0301 Analytical Chemistry