Scholars@Duke publication: Effects of viloxazine with and without alcohol on performance tests related to driving in normal volunteers

Effects of viloxazine with and without alcohol on performance tests related to driving in normal volunteers

Publication , Journal Article

Wilson, WH; Petrie, WM; Ban, TA

Published in: Drug Development Research

1981

The effects of single doses of 50 mg of viloxazine, 100 mg of viloxazine, 50 mg of imipramine, and placebo given alone and in combination with alcohol on perceptual-motor performance potentially related to driving were studied in eight normal subjects. The study design permitted testing of visual reaction time, pursuit rotor performance, and depth perception when blood levels of the active drugs and alcohol were at or near peak. Analyses revealed that the effects of alcohol increased visual reaction time and decreased pursuit rotor performance. None of the drugs produced statistically significant changes on any of the measures. None of the effects of the combined drug and alcohol conditions differed significantly from the effects of alcohol alone.

Duke Scholars

Author William Herman Wilson Psychiatry & Behavioral Sciences, Behavioral Medicine & Neur ...

Published In

Drug Development Research

Publication Date

1981

Volume

Issue

Start / End Page

223 / 228

Related Subject Headings

Pharmacology & Pharmacy
1115 Pharmacology and Pharmaceutical Sciences

Citation

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Wilson, W. H., Petrie, W. M., & Ban, T. A. (1981). Effects of viloxazine with and without alcohol on performance tests related to driving in normal volunteers. Drug Development Research, 1(3), 223–228.

Wilson, W. H., W. M. Petrie, and T. A. Ban. “Effects of viloxazine with and without alcohol on performance tests related to driving in normal volunteers.” Drug Development Research 1, no. 3 (1981): 223–28.

Wilson WH, Petrie WM, Ban TA. Effects of viloxazine with and without alcohol on performance tests related to driving in normal volunteers. Drug Development Research. 1981;1(3):223–8.

Wilson, W. H., et al. “Effects of viloxazine with and without alcohol on performance tests related to driving in normal volunteers.” Drug Development Research, vol. 1, no. 3, 1981, pp. 223–28.

Wilson WH, Petrie WM, Ban TA. Effects of viloxazine with and without alcohol on performance tests related to driving in normal volunteers. Drug Development Research. 1981;1(3):223–228.