Optimal Bayesian two-phase designs
In this paper we present a Bayesian decision theoretic approach to the two-phase design problem. The solution of such sequential decision problems is usually difficult to obtain because of their reliance on preposterior analysis. In overcoming this problem, we adopt the Monte-Carlo-based approach of Müller and Parmigiani (1995) and develop optimal Bayesian designs for two-phase screening tests. A rather attractive feature of the Monte Carlo approach is that it facilitates the preposterior analysis by replacing it with a sequence of scatter plot smoothing/regression techniques and optimization of the corresponding fitted surfaces. The method is illustrated for depression in adolescents using data from past studies. © 1998 Elsevier Science B.V.
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Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Related Subject Headings
- Statistics & Probability
- 4905 Statistics
- 0104 Statistics