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Eligibility and accessibility of magnetic resonance-guided focused ultrasound (MRgFUS) for the treatment of uterine leiomyomas.

Publication ,  Journal Article
Behera, MA; Leong, M; Johnson, L; Brown, H
Published in: Fertil Steril
October 2010

OBJECTIVE: To evaluate patient eligibility and accessibility of magnetic resonance-guided focused ultrasound (MRgFUS) for women with symptomatic uterine leiomyomas who desire conservative therapy. DESIGN: Retrospective analysis of 169 patients referred for minimally invasive treatment of leiomyomas between November 2007 and February 2009. Clinical eligibility for MRgFUS was determined by Food and Drug Administration-based treatment guidelines. All patients underwent pretreatment pelvic imaging to determine candidacy for the procedure. PATIENT(S): Premenopausal women with symptomatic uterine leiomyomas. SETTING: Academic medical center. MAIN OUTCOME MEASURE(S): Eligibility for MRgFUS based on clinical and anatomic patient criteria. RESULT(S): Forty-seven percent of patients (80/169) were determined clinically eligible for the procedure. Of these, 16% of patients (27/169) were found to be eligible for MRgFUS based on imaging results. Overall, the main reasons for ineligibility were very large leiomyomas (8%; 14/169), cost (12%; 21/169), and desired fertility (14%; 23/169). An additional 48% of patients declined MRgFUS for unstated reasons, often after obtaining financial and insurance coverage information. CONCLUSION(S): Currently, many women with leiomyomas are unable to obtain MRgFUS treatment for multiple reasons, including uterine size, desire for fertility, and, most commonly, financial limitations. With increasing clinical experience, further research, and broadened insurance coverage, it may be possible to increase accessibility and expand eligibility criteria for this minimally invasive therapy.

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Published In

Fertil Steril

DOI

EISSN

1556-5653

Publication Date

October 2010

Volume

94

Issue

5

Start / End Page

1864 / 1868

Location

United States

Related Subject Headings

  • Uterine Neoplasms
  • Ultrasonography
  • Ultrasonic Therapy
  • Retrospective Studies
  • Patient Selection
  • Obstetrics & Reproductive Medicine
  • Middle Aged
  • Magnetic Resonance Imaging, Interventional
  • Leiomyoma
  • Insurance Coverage
 

Citation

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Behera, M. A., Leong, M., Johnson, L., & Brown, H. (2010). Eligibility and accessibility of magnetic resonance-guided focused ultrasound (MRgFUS) for the treatment of uterine leiomyomas. Fertil Steril, 94(5), 1864–1868. https://doi.org/10.1016/j.fertnstert.2009.09.063
Behera, Millie A., Madeline Leong, Lauren Johnson, and Haywood Brown. “Eligibility and accessibility of magnetic resonance-guided focused ultrasound (MRgFUS) for the treatment of uterine leiomyomas.Fertil Steril 94, no. 5 (October 2010): 1864–68. https://doi.org/10.1016/j.fertnstert.2009.09.063.
Behera, Millie A., et al. “Eligibility and accessibility of magnetic resonance-guided focused ultrasound (MRgFUS) for the treatment of uterine leiomyomas.Fertil Steril, vol. 94, no. 5, Oct. 2010, pp. 1864–68. Pubmed, doi:10.1016/j.fertnstert.2009.09.063.
Journal cover image

Published In

Fertil Steril

DOI

EISSN

1556-5653

Publication Date

October 2010

Volume

94

Issue

5

Start / End Page

1864 / 1868

Location

United States

Related Subject Headings

  • Uterine Neoplasms
  • Ultrasonography
  • Ultrasonic Therapy
  • Retrospective Studies
  • Patient Selection
  • Obstetrics & Reproductive Medicine
  • Middle Aged
  • Magnetic Resonance Imaging, Interventional
  • Leiomyoma
  • Insurance Coverage