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A simple formula useful for positional cloning.

Publication ,  Journal Article
Durrett, RT; Chen, K-Y; Tanksley, SD
Published in: Genetics
January 2002

We derive a formula for the distribution of the length T of the recombination interval containing a target gene and using N gametes in a region where R kilobases correspond to 1 cM. The formula can be used to calculate the number of meiotic events required to narrow a target gene down to a specific interval size and hence should be useful for planning positional cloning experiments. The predictions of this formula agree well with the results from a number of published experiments in Arabidopsis.

Duke Scholars

Published In

Genetics

DOI

EISSN

1943-2631

ISSN

0016-6731

Publication Date

January 2002

Volume

160

Issue

1

Start / End Page

353 / 355

Related Subject Headings

  • Models, Statistical
  • Models, Genetic
  • Genetic Techniques
  • Developmental Biology
  • Cloning, Molecular
  • Chromosome Mapping
  • 3105 Genetics
  • 3101 Biochemistry and cell biology
  • 0604 Genetics
 

Citation

APA
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ICMJE
MLA
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Durrett, R. T., Chen, K.-Y., & Tanksley, S. D. (2002). A simple formula useful for positional cloning. Genetics, 160(1), 353–355. https://doi.org/10.1093/genetics/160.1.353
Durrett, Richard T., Kai-Yi Chen, and Steven D. Tanksley. “A simple formula useful for positional cloning.Genetics 160, no. 1 (January 2002): 353–55. https://doi.org/10.1093/genetics/160.1.353.
Durrett RT, Chen K-Y, Tanksley SD. A simple formula useful for positional cloning. Genetics. 2002 Jan;160(1):353–5.
Durrett, Richard T., et al. “A simple formula useful for positional cloning.Genetics, vol. 160, no. 1, Jan. 2002, pp. 353–55. Epmc, doi:10.1093/genetics/160.1.353.
Durrett RT, Chen K-Y, Tanksley SD. A simple formula useful for positional cloning. Genetics. 2002 Jan;160(1):353–355.

Published In

Genetics

DOI

EISSN

1943-2631

ISSN

0016-6731

Publication Date

January 2002

Volume

160

Issue

1

Start / End Page

353 / 355

Related Subject Headings

  • Models, Statistical
  • Models, Genetic
  • Genetic Techniques
  • Developmental Biology
  • Cloning, Molecular
  • Chromosome Mapping
  • 3105 Genetics
  • 3101 Biochemistry and cell biology
  • 0604 Genetics