A new stochastic model of microsatellite evolution
Publication
, Journal Article
Durrett, R; Kruglyak, S
Published in: Journal of Applied Probability
January 1, 1999
We introduce a continuous-time Markov chain model for the evolution of microsatellites, simple sequence repeats in DNA. We prove the existence of a unique stationary distribution for our model, and fit the model to data from approximately 106 base pairs of DNA from fruit flies, mice, and humans. The slippage rates from the best fit for our model are consistent with experimental findings.
Duke Scholars
Published In
Journal of Applied Probability
DOI
ISSN
0021-9002
Publication Date
January 1, 1999
Volume
36
Issue
3
Start / End Page
621 / 631
Related Subject Headings
- Statistics & Probability
- 4905 Statistics
- 4901 Applied mathematics
- 0104 Statistics
- 0102 Applied Mathematics
Citation
APA
Chicago
ICMJE
MLA
NLM
Durrett, R., & Kruglyak, S. (1999). A new stochastic model of microsatellite evolution. Journal of Applied Probability, 36(3), 621–631. https://doi.org/10.1017/S0021900200017447
Durrett, R., and S. Kruglyak. “A new stochastic model of microsatellite evolution.” Journal of Applied Probability 36, no. 3 (January 1, 1999): 621–31. https://doi.org/10.1017/S0021900200017447.
Durrett R, Kruglyak S. A new stochastic model of microsatellite evolution. Journal of Applied Probability. 1999 Jan 1;36(3):621–31.
Durrett, R., and S. Kruglyak. “A new stochastic model of microsatellite evolution.” Journal of Applied Probability, vol. 36, no. 3, Jan. 1999, pp. 621–31. Scopus, doi:10.1017/S0021900200017447.
Durrett R, Kruglyak S. A new stochastic model of microsatellite evolution. Journal of Applied Probability. 1999 Jan 1;36(3):621–631.
Published In
Journal of Applied Probability
DOI
ISSN
0021-9002
Publication Date
January 1, 1999
Volume
36
Issue
3
Start / End Page
621 / 631
Related Subject Headings
- Statistics & Probability
- 4905 Statistics
- 4901 Applied mathematics
- 0104 Statistics
- 0102 Applied Mathematics