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Intended single-modality management of T1 and T2 tonsillar carcinomas: retrospective comparison of radical tonsillectomy vs radiation from a single institution.

Publication ,  Journal Article
Lamarre, ED; Seth, R; Lorenz, RR; Esclamado, R; Adelstein, DJ; Rodriguez, CP; Saxton, J; Scharpf, J
Published in: Am J Otolaryngol
2012

BACKGROUND: T1 and T2 tonsillar squamous cell cancer with limited neck disease can be managed with single-modality radiation or surgery. Over 11 years, 17 patients underwent radical tonsillectomies; and 33 patients underwent radiation-based treatments for T1 and T2 and N0 to N2a tonsil cancer. Patients were intended to receive single-modality treatment based on presentation; however, some ultimately received adjuvant treatments. METHODS: A retrospective chart review to compare overall survival (OS), disease-specific survival (DSS), and locoregional control (LRC) between the groups was used. RESULTS: In surgical group, of 17 patients, 11 underwent surgery alone, 3 underwent surgery and radiation, and 3 underwent surgery with concurrent chemoradiation. Five-year OS for the surgical and radiation groups was 93% and 72%, respectively (no significance achieved). Five-year DSS rates (93% and 80%) and LRC (69% and 89%) similarly did not yield any significant difference. CONCLUSION: Surgery remains a viable option in the management of T1 and T2 tonsillar cancers with comparable LRC, OS, and DSS.

Duke Scholars

Published In

Am J Otolaryngol

DOI

EISSN

1532-818X

Publication Date

2012

Volume

33

Issue

1

Start / End Page

98 / 103

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Tonsillectomy
  • Tonsillar Neoplasms
  • Survival Rate
  • Retrospective Studies
  • Radiotherapy Dosage
  • Otorhinolaryngology
  • Neoplasm Staging
  • Neoplasm Grading
  • Middle Aged
 

Citation

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Chicago
ICMJE
MLA
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Lamarre, E. D., Seth, R., Lorenz, R. R., Esclamado, R., Adelstein, D. J., Rodriguez, C. P., … Scharpf, J. (2012). Intended single-modality management of T1 and T2 tonsillar carcinomas: retrospective comparison of radical tonsillectomy vs radiation from a single institution. Am J Otolaryngol, 33(1), 98–103. https://doi.org/10.1016/j.amjoto.2011.02.005
Lamarre, Eric D., Rahul Seth, Robert R. Lorenz, Ramon Esclamado, David J. Adelstein, Cristina P. Rodriguez, Jerrold Saxton, and Joseph Scharpf. “Intended single-modality management of T1 and T2 tonsillar carcinomas: retrospective comparison of radical tonsillectomy vs radiation from a single institution.Am J Otolaryngol 33, no. 1 (2012): 98–103. https://doi.org/10.1016/j.amjoto.2011.02.005.
Lamarre ED, Seth R, Lorenz RR, Esclamado R, Adelstein DJ, Rodriguez CP, et al. Intended single-modality management of T1 and T2 tonsillar carcinomas: retrospective comparison of radical tonsillectomy vs radiation from a single institution. Am J Otolaryngol. 2012;33(1):98–103.
Lamarre, Eric D., et al. “Intended single-modality management of T1 and T2 tonsillar carcinomas: retrospective comparison of radical tonsillectomy vs radiation from a single institution.Am J Otolaryngol, vol. 33, no. 1, 2012, pp. 98–103. Pubmed, doi:10.1016/j.amjoto.2011.02.005.
Lamarre ED, Seth R, Lorenz RR, Esclamado R, Adelstein DJ, Rodriguez CP, Saxton J, Scharpf J. Intended single-modality management of T1 and T2 tonsillar carcinomas: retrospective comparison of radical tonsillectomy vs radiation from a single institution. Am J Otolaryngol. 2012;33(1):98–103.
Journal cover image

Published In

Am J Otolaryngol

DOI

EISSN

1532-818X

Publication Date

2012

Volume

33

Issue

1

Start / End Page

98 / 103

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Tonsillectomy
  • Tonsillar Neoplasms
  • Survival Rate
  • Retrospective Studies
  • Radiotherapy Dosage
  • Otorhinolaryngology
  • Neoplasm Staging
  • Neoplasm Grading
  • Middle Aged