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Guanazole (NSC 1895) in the treatment of childhood leukemia

Publication ,  Journal Article
Land, VJ; Falletta, JM; McMillan, CW; Williams, TE
Published in: CANCER CHEMOTHER.REP.
December 1, 1974

Twenty six children with late stage acute leukemia in relapse were treated with a total of 48 courses of guanazole at a dose of 15 g/m2/dy for 5 days, given approximately every 2 wk. No complete or partial remissions were achieved in 18 evaluable patients, although 2 of 3 evaluable patients with acute myelogenous leukemia and one of 15 evaluable patients with acute lymphoblastic leukemia showed a transient decrease in the number and percentage of blast cells in the bone marrow and peripheral blood. Bone marrow depression, attributed to the guanazole therapy, occurred in all but 6 evaluable patients.

Duke Scholars

Published In

CANCER CHEMOTHER.REP.

Publication Date

December 1, 1974

Volume

58

Issue

5

Start / End Page

715 / 717
 

Citation

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MLA
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Land, V. J., Falletta, J. M., McMillan, C. W., & Williams, T. E. (1974). Guanazole (NSC 1895) in the treatment of childhood leukemia. CANCER CHEMOTHER.REP., 58(5), 715–717.
Land, V. J., J. M. Falletta, C. W. McMillan, and T. E. Williams. “Guanazole (NSC 1895) in the treatment of childhood leukemia.” CANCER CHEMOTHER.REP. 58, no. 5 (December 1, 1974): 715–17.
Land VJ, Falletta JM, McMillan CW, Williams TE. Guanazole (NSC 1895) in the treatment of childhood leukemia. CANCER CHEMOTHERREP. 1974 Dec 1;58(5):715–7.
Land, V. J., et al. “Guanazole (NSC 1895) in the treatment of childhood leukemia.” CANCER CHEMOTHER.REP., vol. 58, no. 5, Dec. 1974, pp. 715–17.
Land VJ, Falletta JM, McMillan CW, Williams TE. Guanazole (NSC 1895) in the treatment of childhood leukemia. CANCER CHEMOTHERREP. 1974 Dec 1;58(5):715–717.

Published In

CANCER CHEMOTHER.REP.

Publication Date

December 1, 1974

Volume

58

Issue

5

Start / End Page

715 / 717