Translocation (X;19) with involvement of the inactive X chromosome in oligoblastic granulocytic leukemia.
Publication
, Journal Article
Gibas, Z; Gibas, LM; Filomena, CA; Sprandio, J; Jackson, LG
Published in: Cancer Genet Cytogenet
October 15, 1988
A 72-year-old female with metastatic breast cancer developed oligoblastic granulocytic leukemia 6 months after initiation of chemotherapy. Cytogenetic examination of the bone marrow cells revealed a balanced t(X;19)(q12;q13.3) as the sole abnormality in 50% of the metaphases. The remaining cells showed a normal female karyotype. The der(19) chromosome displayed consistent folding in the Xq13-q23 region in all metaphases, indicating involvement of the inactive X chromosome in translocation.
Duke Scholars
Published In
Cancer Genet Cytogenet
DOI
ISSN
0165-4608
Publication Date
October 15, 1988
Volume
35
Issue
2
Start / End Page
237 / 242
Location
United States
Related Subject Headings
- X Chromosome
- Translocation, Genetic
- Oncology & Carcinogenesis
- Leukemia, Myeloid
- Karyotyping
- Humans
- Female
- Dosage Compensation, Genetic
- Chromosomes, Human, Pair 19
- Aged
Citation
APA
Chicago
ICMJE
MLA
NLM
Gibas, Z., Gibas, L. M., Filomena, C. A., Sprandio, J., & Jackson, L. G. (1988). Translocation (X;19) with involvement of the inactive X chromosome in oligoblastic granulocytic leukemia. Cancer Genet Cytogenet, 35(2), 237–242. https://doi.org/10.1016/0165-4608(88)90246-4
Gibas, Z., L. M. Gibas, C. A. Filomena, J. Sprandio, and L. G. Jackson. “Translocation (X;19) with involvement of the inactive X chromosome in oligoblastic granulocytic leukemia.” Cancer Genet Cytogenet 35, no. 2 (October 15, 1988): 237–42. https://doi.org/10.1016/0165-4608(88)90246-4.
Gibas Z, Gibas LM, Filomena CA, Sprandio J, Jackson LG. Translocation (X;19) with involvement of the inactive X chromosome in oligoblastic granulocytic leukemia. Cancer Genet Cytogenet. 1988 Oct 15;35(2):237–42.
Gibas, Z., et al. “Translocation (X;19) with involvement of the inactive X chromosome in oligoblastic granulocytic leukemia.” Cancer Genet Cytogenet, vol. 35, no. 2, Oct. 1988, pp. 237–42. Pubmed, doi:10.1016/0165-4608(88)90246-4.
Gibas Z, Gibas LM, Filomena CA, Sprandio J, Jackson LG. Translocation (X;19) with involvement of the inactive X chromosome in oligoblastic granulocytic leukemia. Cancer Genet Cytogenet. 1988 Oct 15;35(2):237–242.
Published In
Cancer Genet Cytogenet
DOI
ISSN
0165-4608
Publication Date
October 15, 1988
Volume
35
Issue
2
Start / End Page
237 / 242
Location
United States
Related Subject Headings
- X Chromosome
- Translocation, Genetic
- Oncology & Carcinogenesis
- Leukemia, Myeloid
- Karyotyping
- Humans
- Female
- Dosage Compensation, Genetic
- Chromosomes, Human, Pair 19
- Aged