Peg-bovine hemoglobin: Safety in a canine dehydrated hypovolemic- hemorrhagic shock model
Publication
, Journal Article
Nho, K; Glower, D; Bredehoeft, S; Shankar, H; Shorr, R; Abuchowski, A
Published in: Biomaterials, Artificial Cells, and Immobilization Biotechnology
1992
An initial evaluation of PEG-bHb was performed using a modified hypovolemic shock model. PEG-bHb had a substantially longer intravascular half-life than native Hb and no measurable hemoglobinuria was observed in the canine. PEG-bHb allowed successful resuscitation with an oxygen carrying capacity of 14-22% over that of lactated Ringer's solution.
Duke Scholars
Published In
Biomaterials, Artificial Cells, and Immobilization Biotechnology
Publication Date
1992
Volume
20
Issue
2-4
Start / End Page
511 / 524
Citation
APA
Chicago
ICMJE
MLA
NLM
Nho, K., Glower, D., Bredehoeft, S., Shankar, H., Shorr, R., & Abuchowski, A. (1992). Peg-bovine hemoglobin: Safety in a canine dehydrated hypovolemic- hemorrhagic shock model. Biomaterials, Artificial Cells, and Immobilization Biotechnology, 20(2–4), 511–524.
Nho, K., D. Glower, S. Bredehoeft, H. Shankar, R. Shorr, and A. Abuchowski. “Peg-bovine hemoglobin: Safety in a canine dehydrated hypovolemic- hemorrhagic shock model.” Biomaterials, Artificial Cells, and Immobilization Biotechnology 20, no. 2–4 (1992): 511–24.
Nho K, Glower D, Bredehoeft S, Shankar H, Shorr R, Abuchowski A. Peg-bovine hemoglobin: Safety in a canine dehydrated hypovolemic- hemorrhagic shock model. Biomaterials, Artificial Cells, and Immobilization Biotechnology. 1992;20(2–4):511–24.
Nho, K., et al. “Peg-bovine hemoglobin: Safety in a canine dehydrated hypovolemic- hemorrhagic shock model.” Biomaterials, Artificial Cells, and Immobilization Biotechnology, vol. 20, no. 2–4, 1992, pp. 511–24.
Nho K, Glower D, Bredehoeft S, Shankar H, Shorr R, Abuchowski A. Peg-bovine hemoglobin: Safety in a canine dehydrated hypovolemic- hemorrhagic shock model. Biomaterials, Artificial Cells, and Immobilization Biotechnology. 1992;20(2–4):511–524.
Published In
Biomaterials, Artificial Cells, and Immobilization Biotechnology
Publication Date
1992
Volume
20
Issue
2-4
Start / End Page
511 / 524