Skip to main content
release_alert
Welcome to the new Scholars 3.0! Read about new features and let us know what you think.
cancel
Journal cover image

Impact of early, late, and no ST-segment resolution measured by continuous ST Holter monitoring on left ventricular ejection fraction and infarct size as determined by cardiovascular magnetic resonance imaging.

Publication ,  Journal Article
Haeck, JDE; Verouden, NJW; Kuijt, WJ; Koch, KT; Majidi, M; Hirsch, A; Tijssen, JGP; Krucoff, MW; De Winter, RJ
Published in: J Electrocardiol
2011

BACKGROUND: The goal of this study is to determine the predictive value of ST-segment resolution (STR) early after percutaneous coronary intervention (PCI), late STR, and no STR for left ventricular ejection fraction (LVEF) and infarct size (IS) by cardiovascular magnetic resonance (CMR) at follow-up in patients with ST-segment elevation myocardial infarction. METHODS: The analysis included 199 patients who were enrolled in the PRoximal Embolic Protection in Acute myocardial infarction and Resolution of ST-Elevation trial and in whom both continuous ST Holter and CMR at follow-up were available. Patients were stratified into 3 groups: (1) early complete (≥70%) STR measured immediately after last contrast injection (n = 113); (2) late complete STR (n = 52), defined as complete STR from 30 to 240 minutes after PCI; and (3) no complete STR after 240 minutes (n = 34). RESULTS: Patients with early STR had more preserved LVEF and smaller IS compared to patients with late STR or no STR (LVEF: early STR, 54% ± 8%; late STR, 46% ± 13%; no STR, 43% ± 11%; and IS: 3.9 ± 3.3 g/m(2); 8.0 ± 6.9 g/m(2); 12.0 ± 6.0 g/m(2); respectively; all P < .0001). Early STR was independently predictive for LVEF (β = 8.5; P = .0005) and IS (β = -7.0; P < .0001). Late STR was not predictive for LVEF (β = 1.6; P = .51) but predictive for IS (β = -3.5; P = .003). CONCLUSIONS: Patients with early complete STR after primary PCI have better preserved LVEF and smaller IS. Patients with late complete STR do not have better preserved LVEF but do have smaller IS. ST-segment resolution is a strong, independent predictor of LVEF and IS as assessed by CMR.

Duke Scholars

Published In

J Electrocardiol

DOI

EISSN

1532-8430

Publication Date

2011

Volume

44

Issue

1

Start / End Page

36 / 41

Location

United States

Related Subject Headings

  • Ventricular Dysfunction, Left
  • Stroke Volume
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Myocardial Infarction
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging, Cine
  • Humans
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Haeck, J. D. E., Verouden, N. J. W., Kuijt, W. J., Koch, K. T., Majidi, M., Hirsch, A., … De Winter, R. J. (2011). Impact of early, late, and no ST-segment resolution measured by continuous ST Holter monitoring on left ventricular ejection fraction and infarct size as determined by cardiovascular magnetic resonance imaging. J Electrocardiol, 44(1), 36–41. https://doi.org/10.1016/j.jelectrocard.2010.08.004
Haeck, Joost D. E., Niels J. W. Verouden, Wichert J. Kuijt, Karel T. Koch, Mohamed Majidi, Alexander Hirsch, Jan G. P. Tijssen, Mitchell W. Krucoff, and Robbert J. De Winter. “Impact of early, late, and no ST-segment resolution measured by continuous ST Holter monitoring on left ventricular ejection fraction and infarct size as determined by cardiovascular magnetic resonance imaging.J Electrocardiol 44, no. 1 (2011): 36–41. https://doi.org/10.1016/j.jelectrocard.2010.08.004.
Haeck JDE, Verouden NJW, Kuijt WJ, Koch KT, Majidi M, Hirsch A, Tijssen JGP, Krucoff MW, De Winter RJ. Impact of early, late, and no ST-segment resolution measured by continuous ST Holter monitoring on left ventricular ejection fraction and infarct size as determined by cardiovascular magnetic resonance imaging. J Electrocardiol. 2011;44(1):36–41.
Journal cover image

Published In

J Electrocardiol

DOI

EISSN

1532-8430

Publication Date

2011

Volume

44

Issue

1

Start / End Page

36 / 41

Location

United States

Related Subject Headings

  • Ventricular Dysfunction, Left
  • Stroke Volume
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Myocardial Infarction
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging, Cine
  • Humans
  • Female