Biochemical mechanisms of β-adrenergic receptor regulation
Publication
, Journal Article
Sibley, DR; Lefkowitz, RJ
Published in: ISI Atlas of Science: Pharmacology
January 1, 1988
β-Adrenergic receptors for catecholamines, which stimulate adenylate cyclase, are prototypes of a large gene family of receptors which interact with guanine nucleotide regulatory proteins. The function of such receptors is dynamically regulated so that stimulation by agonists is followed by desensitization. An important mechanism for such regulation appears to be covalent modification of the receptors by phosphorylation catalyzed by a variety of protein kinases.
Duke Scholars
Published In
ISI Atlas of Science: Pharmacology
ISSN
0890-9083
Publication Date
January 1, 1988
Volume
2
Issue
1
Start / End Page
66 / 70
Citation
APA
Chicago
ICMJE
MLA
NLM
Sibley, D. R., & Lefkowitz, R. J. (1988). Biochemical mechanisms of β-adrenergic receptor regulation. ISI Atlas of Science: Pharmacology, 2(1), 66–70.
Sibley, D. R., and R. J. Lefkowitz. “Biochemical mechanisms of β-adrenergic receptor regulation.” ISI Atlas of Science: Pharmacology 2, no. 1 (January 1, 1988): 66–70.
Sibley DR, Lefkowitz RJ. Biochemical mechanisms of β-adrenergic receptor regulation. ISI Atlas of Science: Pharmacology. 1988 Jan 1;2(1):66–70.
Sibley, D. R., and R. J. Lefkowitz. “Biochemical mechanisms of β-adrenergic receptor regulation.” ISI Atlas of Science: Pharmacology, vol. 2, no. 1, Jan. 1988, pp. 66–70.
Sibley DR, Lefkowitz RJ. Biochemical mechanisms of β-adrenergic receptor regulation. ISI Atlas of Science: Pharmacology. 1988 Jan 1;2(1):66–70.
Published In
ISI Atlas of Science: Pharmacology
ISSN
0890-9083
Publication Date
January 1, 1988
Volume
2
Issue
1
Start / End Page
66 / 70