Mapping of the mouse Rar loci encoding retinoic acid receptors RAR alpha, RAR beta and RAR gamma.
Publication
, Journal Article
Taketo, M; Hoopes, C; Howard, TA; Linney, E; Seldin, MF
Published in: Jpn J Genet
June 1993
Nuclear retinoic acid receptors RAR alpha, RAR beta and RAR gamma are transcription factors that bind all-trans retinoic acid as their ligand and mediate its action by activating particular set of genes that contain retinoic acid responsive elements in their promoter-enhancers. We have mapped genetic loci for these genes using restriction fragment length variants (RFLVs) in interspecific backcross mice. None of the Rar loci cosegregated with each other or with the new subclass of retinoid receptors, Rxr loci. Rara mapped to mChr 11, Rarb mapped to mChr 14, and Rarg mapped to mChr 15. The results are consistent with the previous reports and the human data in terms of syntenic homology between mouse and human chromosomes.
Duke Scholars
Published In
Jpn J Genet
DOI
ISSN
0021-504X
Publication Date
June 1993
Volume
68
Issue
3
Start / End Page
175 / 184
Location
Japan
Related Subject Headings
- Receptors, Retinoic Acid
- Plant Biology & Botany
- Mice, Inbred C3H
- Mice
- Haplotypes
- Crosses, Genetic
- Chromosome Mapping
- Animals
- 3105 Genetics
- 0604 Genetics
Citation
APA
Chicago
ICMJE
MLA
NLM
Taketo, M., Hoopes, C., Howard, T. A., Linney, E., & Seldin, M. F. (1993). Mapping of the mouse Rar loci encoding retinoic acid receptors RAR alpha, RAR beta and RAR gamma. Jpn J Genet, 68(3), 175–184. https://doi.org/10.1266/jjg.68.175
Taketo, M., C. Hoopes, T. A. Howard, E. Linney, and M. F. Seldin. “Mapping of the mouse Rar loci encoding retinoic acid receptors RAR alpha, RAR beta and RAR gamma.” Jpn J Genet 68, no. 3 (June 1993): 175–84. https://doi.org/10.1266/jjg.68.175.
Taketo M, Hoopes C, Howard TA, Linney E, Seldin MF. Mapping of the mouse Rar loci encoding retinoic acid receptors RAR alpha, RAR beta and RAR gamma. Jpn J Genet. 1993 Jun;68(3):175–84.
Taketo, M., et al. “Mapping of the mouse Rar loci encoding retinoic acid receptors RAR alpha, RAR beta and RAR gamma.” Jpn J Genet, vol. 68, no. 3, June 1993, pp. 175–84. Pubmed, doi:10.1266/jjg.68.175.
Taketo M, Hoopes C, Howard TA, Linney E, Seldin MF. Mapping of the mouse Rar loci encoding retinoic acid receptors RAR alpha, RAR beta and RAR gamma. Jpn J Genet. 1993 Jun;68(3):175–184.
Published In
Jpn J Genet
DOI
ISSN
0021-504X
Publication Date
June 1993
Volume
68
Issue
3
Start / End Page
175 / 184
Location
Japan
Related Subject Headings
- Receptors, Retinoic Acid
- Plant Biology & Botany
- Mice, Inbred C3H
- Mice
- Haplotypes
- Crosses, Genetic
- Chromosome Mapping
- Animals
- 3105 Genetics
- 0604 Genetics