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Mapping of the mouse Rar loci encoding retinoic acid receptors RAR alpha, RAR beta and RAR gamma.

Publication ,  Journal Article
Taketo, M; Hoopes, C; Howard, TA; Linney, E; Seldin, MF
Published in: Jpn J Genet
June 1993

Nuclear retinoic acid receptors RAR alpha, RAR beta and RAR gamma are transcription factors that bind all-trans retinoic acid as their ligand and mediate its action by activating particular set of genes that contain retinoic acid responsive elements in their promoter-enhancers. We have mapped genetic loci for these genes using restriction fragment length variants (RFLVs) in interspecific backcross mice. None of the Rar loci cosegregated with each other or with the new subclass of retinoid receptors, Rxr loci. Rara mapped to mChr 11, Rarb mapped to mChr 14, and Rarg mapped to mChr 15. The results are consistent with the previous reports and the human data in terms of syntenic homology between mouse and human chromosomes.

Duke Scholars

Published In

Jpn J Genet

DOI

ISSN

0021-504X

Publication Date

June 1993

Volume

68

Issue

3

Start / End Page

175 / 184

Location

Japan

Related Subject Headings

  • Receptors, Retinoic Acid
  • Plant Biology & Botany
  • Mice, Inbred C3H
  • Mice
  • Haplotypes
  • Crosses, Genetic
  • Chromosome Mapping
  • Animals
  • 3105 Genetics
  • 0604 Genetics
 

Citation

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ICMJE
MLA
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Taketo, M., Hoopes, C., Howard, T. A., Linney, E., & Seldin, M. F. (1993). Mapping of the mouse Rar loci encoding retinoic acid receptors RAR alpha, RAR beta and RAR gamma. Jpn J Genet, 68(3), 175–184. https://doi.org/10.1266/jjg.68.175
Taketo, M., C. Hoopes, T. A. Howard, E. Linney, and M. F. Seldin. “Mapping of the mouse Rar loci encoding retinoic acid receptors RAR alpha, RAR beta and RAR gamma.Jpn J Genet 68, no. 3 (June 1993): 175–84. https://doi.org/10.1266/jjg.68.175.
Taketo M, Hoopes C, Howard TA, Linney E, Seldin MF. Mapping of the mouse Rar loci encoding retinoic acid receptors RAR alpha, RAR beta and RAR gamma. Jpn J Genet. 1993 Jun;68(3):175–84.
Taketo, M., et al. “Mapping of the mouse Rar loci encoding retinoic acid receptors RAR alpha, RAR beta and RAR gamma.Jpn J Genet, vol. 68, no. 3, June 1993, pp. 175–84. Pubmed, doi:10.1266/jjg.68.175.
Taketo M, Hoopes C, Howard TA, Linney E, Seldin MF. Mapping of the mouse Rar loci encoding retinoic acid receptors RAR alpha, RAR beta and RAR gamma. Jpn J Genet. 1993 Jun;68(3):175–184.

Published In

Jpn J Genet

DOI

ISSN

0021-504X

Publication Date

June 1993

Volume

68

Issue

3

Start / End Page

175 / 184

Location

Japan

Related Subject Headings

  • Receptors, Retinoic Acid
  • Plant Biology & Botany
  • Mice, Inbred C3H
  • Mice
  • Haplotypes
  • Crosses, Genetic
  • Chromosome Mapping
  • Animals
  • 3105 Genetics
  • 0604 Genetics