Escherichia coli K-12 clones that overproduce dam methylase are hypermutable.
Publication
, Journal Article
Herman, GE; Modrich, P
Published in: J Bacteriol
January 1981
A strain of Escherichia coli K-12 that overproduces dam methylase 50-fold was found to be hypermutable, and mutations which resulted in loss of excess methylase activity restored mutation frequencies to wild-type levels. These results are consistent with involvement of this deoxyribonucleic acid methylase in mismatch correction.
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Published In
J Bacteriol
DOI
ISSN
0021-9193
Publication Date
January 1981
Volume
145
Issue
1
Start / End Page
644 / 646
Location
United States
Related Subject Headings
- Mutation
- Microbiology
- Methyltransferases
- Escherichia coli
- DNA, Bacterial
- DNA Repair
- DNA (Cytosine-5-)-Methyltransferases
- Cloning, Molecular
- 32 Biomedical and clinical sciences
- 31 Biological sciences
Citation
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Chicago
ICMJE
MLA
NLM
Herman, G. E., & Modrich, P. (1981). Escherichia coli K-12 clones that overproduce dam methylase are hypermutable. J Bacteriol, 145(1), 644–646. https://doi.org/10.1128/jb.145.1.644-646.1981
Herman, G. E., and P. Modrich. “Escherichia coli K-12 clones that overproduce dam methylase are hypermutable.” J Bacteriol 145, no. 1 (January 1981): 644–46. https://doi.org/10.1128/jb.145.1.644-646.1981.
Herman GE, Modrich P. Escherichia coli K-12 clones that overproduce dam methylase are hypermutable. J Bacteriol. 1981 Jan;145(1):644–6.
Herman, G. E., and P. Modrich. “Escherichia coli K-12 clones that overproduce dam methylase are hypermutable.” J Bacteriol, vol. 145, no. 1, Jan. 1981, pp. 644–46. Pubmed, doi:10.1128/jb.145.1.644-646.1981.
Herman GE, Modrich P. Escherichia coli K-12 clones that overproduce dam methylase are hypermutable. J Bacteriol. 1981 Jan;145(1):644–646.
Published In
J Bacteriol
DOI
ISSN
0021-9193
Publication Date
January 1981
Volume
145
Issue
1
Start / End Page
644 / 646
Location
United States
Related Subject Headings
- Mutation
- Microbiology
- Methyltransferases
- Escherichia coli
- DNA, Bacterial
- DNA Repair
- DNA (Cytosine-5-)-Methyltransferases
- Cloning, Molecular
- 32 Biomedical and clinical sciences
- 31 Biological sciences