
Argatroban for anticoagulation during cardiopulmonary bypass in an infant.
Publication
, Journal Article
Dyke, PC; Russo, P; Mureebe, L; Russo, J; Tobias, JD
Published in: Paediatr Anaesth
April 2005
Heparin induced thrombocytopenia (HIT) is a rare, but potentially life-threatening complication of heparin therapy. In patients with HIT, alternative means of anticoagulation are necessary. The authors present an infant with HIT who required anticoagulation during cardiopulmonary bypass for tricuspid valve excision in the treatment of bacterial endocarditis. The direct thrombin inhibitor, argatroban, was successfully used. Previous reports regarding the use of argatroban and other nonheparin anticoagulants for anticoagulation are reviewed and suggestions regarding argatroban dosing in infants are presented.
Duke Scholars
Published In
Paediatr Anaesth
DOI
ISSN
1155-5645
Publication Date
April 2005
Volume
15
Issue
4
Start / End Page
328 / 333
Location
France
Related Subject Headings
- Tricuspid Valve
- Thrombocytopenia
- Sulfonamides
- Splenomegaly
- Pipecolic Acids
- Male
- Intraoperative Complications
- Infant
- Humans
- Hepatomegaly
Citation
APA
Chicago
ICMJE
MLA
NLM
Dyke, P. C., Russo, P., Mureebe, L., Russo, J., & Tobias, J. D. (2005). Argatroban for anticoagulation during cardiopulmonary bypass in an infant. Paediatr Anaesth, 15(4), 328–333. https://doi.org/10.1111/j.1460-9592.2005.01417.x
Dyke, Peter C., Pierantonio Russo, Leila Mureebe, Joanne Russo, and Joseph D. Tobias. “Argatroban for anticoagulation during cardiopulmonary bypass in an infant.” Paediatr Anaesth 15, no. 4 (April 2005): 328–33. https://doi.org/10.1111/j.1460-9592.2005.01417.x.
Dyke PC, Russo P, Mureebe L, Russo J, Tobias JD. Argatroban for anticoagulation during cardiopulmonary bypass in an infant. Paediatr Anaesth. 2005 Apr;15(4):328–33.
Dyke, Peter C., et al. “Argatroban for anticoagulation during cardiopulmonary bypass in an infant.” Paediatr Anaesth, vol. 15, no. 4, Apr. 2005, pp. 328–33. Pubmed, doi:10.1111/j.1460-9592.2005.01417.x.
Dyke PC, Russo P, Mureebe L, Russo J, Tobias JD. Argatroban for anticoagulation during cardiopulmonary bypass in an infant. Paediatr Anaesth. 2005 Apr;15(4):328–333.

Published In
Paediatr Anaesth
DOI
ISSN
1155-5645
Publication Date
April 2005
Volume
15
Issue
4
Start / End Page
328 / 333
Location
France
Related Subject Headings
- Tricuspid Valve
- Thrombocytopenia
- Sulfonamides
- Splenomegaly
- Pipecolic Acids
- Male
- Intraoperative Complications
- Infant
- Humans
- Hepatomegaly