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Hypercoagulable states: a review.

Publication ,  Journal Article
Johnson, CM; Mureebe, L; Silver, D
Published in: Vasc Endovascular Surg
2005

Vascular surgeons are often asked to evaluate patients with recurrent thromboses or thromboses in unusual locations either arterial or venous. There may be obvious inciting factors, but in many of these patients the possibility of a previously undiagnosed hypercoagulable state must be considered. Hypercoagulable states can be acquired (smoking, medication, change in physiologic status as occurs with pregnancy) or congenital. Congenital hypercoagulable disorders are more prevalent in families or patients with a history of thromboembolic events early in life or multiple miscarriages and include conditions such as protein C or S deficiencies, factor V Leiden mutation, and prothrombin gene variant. This article reviews the hypercoagulable states that are encountered in clinical practice as well as guidelines for testing and goals of therapy.

Duke Scholars

Published In

Vasc Endovascular Surg

DOI

ISSN

1538-5744

Publication Date

2005

Volume

39

Issue

2

Start / End Page

123 / 133

Location

United States

Related Subject Headings

  • Thrombophilia
  • Thrombocytopenia
  • Smoking
  • Skin
  • Pregnancy
  • Necrosis
  • Humans
  • Female
  • Contraceptives, Oral
  • Cardiovascular System & Hematology
 

Citation

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Johnson, C. M., Mureebe, L., & Silver, D. (2005). Hypercoagulable states: a review. Vasc Endovascular Surg, 39(2), 123–133. https://doi.org/10.1177/153857440503900201
Johnson, Colleen M., Leila Mureebe, and Donald Silver. “Hypercoagulable states: a review.Vasc Endovascular Surg 39, no. 2 (2005): 123–33. https://doi.org/10.1177/153857440503900201.
Johnson CM, Mureebe L, Silver D. Hypercoagulable states: a review. Vasc Endovascular Surg. 2005;39(2):123–33.
Johnson, Colleen M., et al. “Hypercoagulable states: a review.Vasc Endovascular Surg, vol. 39, no. 2, 2005, pp. 123–33. Pubmed, doi:10.1177/153857440503900201.
Johnson CM, Mureebe L, Silver D. Hypercoagulable states: a review. Vasc Endovascular Surg. 2005;39(2):123–133.
Journal cover image

Published In

Vasc Endovascular Surg

DOI

ISSN

1538-5744

Publication Date

2005

Volume

39

Issue

2

Start / End Page

123 / 133

Location

United States

Related Subject Headings

  • Thrombophilia
  • Thrombocytopenia
  • Smoking
  • Skin
  • Pregnancy
  • Necrosis
  • Humans
  • Female
  • Contraceptives, Oral
  • Cardiovascular System & Hematology