Cytokine therapy of cutaneous T-cell lymphoma: interferons, interleukin-12, and interleukin-2.
Publication
, Journal Article
Rook, AH; Kuzel, TM; Olsen, EA
Published in: Hematol Oncol Clin North Am
December 2003
It is well accepted that cutaneous T-cell lymphomas (CTCL), including mycosis fungoides and Sézary syndrome, represent lymphomas that are highly responsive to immune modifying agents. Furthermore, the recent emphasis on the use of cytokine-related therapeutics is based upon the exceedingly important role of the host immune response in effecting progression of disease. In this article we discuss the data that support the importance of the host immune response in the control of progression of CTCL and the role that cytokine therapy has in supporting the host immune response and the effects of this approach to induce regression of skin and systemic disease.
Duke Scholars
Published In
Hematol Oncol Clin North Am
DOI
ISSN
0889-8588
Publication Date
December 2003
Volume
17
Issue
6
Start / End Page
1435 / ix
Location
United States
Related Subject Headings
- Skin Neoplasms
- Recombinant Proteins
- Oncology & Carcinogenesis
- Lymphoma, T-Cell, Cutaneous
- Interleukin-2
- Interleukin-12
- Interferons
- Immunologic Factors
- Humans
- Disease Progression
Citation
APA
Chicago
ICMJE
MLA
NLM
Rook, A. H., Kuzel, T. M., & Olsen, E. A. (2003). Cytokine therapy of cutaneous T-cell lymphoma: interferons, interleukin-12, and interleukin-2. Hematol Oncol Clin North Am, 17(6), 1435–ix. https://doi.org/10.1016/s0889-8588(03)00109-6
Rook, Alain H., Timothy M. Kuzel, and Elise A. Olsen. “Cytokine therapy of cutaneous T-cell lymphoma: interferons, interleukin-12, and interleukin-2.” Hematol Oncol Clin North Am 17, no. 6 (December 2003): 1435–ix. https://doi.org/10.1016/s0889-8588(03)00109-6.
Rook AH, Kuzel TM, Olsen EA. Cytokine therapy of cutaneous T-cell lymphoma: interferons, interleukin-12, and interleukin-2. Hematol Oncol Clin North Am. 2003 Dec;17(6):1435–ix.
Rook, Alain H., et al. “Cytokine therapy of cutaneous T-cell lymphoma: interferons, interleukin-12, and interleukin-2.” Hematol Oncol Clin North Am, vol. 17, no. 6, Dec. 2003, pp. 1435–ix. Pubmed, doi:10.1016/s0889-8588(03)00109-6.
Rook AH, Kuzel TM, Olsen EA. Cytokine therapy of cutaneous T-cell lymphoma: interferons, interleukin-12, and interleukin-2. Hematol Oncol Clin North Am. 2003 Dec;17(6):1435–ix.
Published In
Hematol Oncol Clin North Am
DOI
ISSN
0889-8588
Publication Date
December 2003
Volume
17
Issue
6
Start / End Page
1435 / ix
Location
United States
Related Subject Headings
- Skin Neoplasms
- Recombinant Proteins
- Oncology & Carcinogenesis
- Lymphoma, T-Cell, Cutaneous
- Interleukin-2
- Interleukin-12
- Interferons
- Immunologic Factors
- Humans
- Disease Progression