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The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeast.

Publication ,  Journal Article
Ritchie, KB; Petes, TD
Published in: Genetics
May 2000

The Mre11p/Rad50p/Xrs2p complex is involved in the repair of double-strand DNA breaks, nonhomologous end joining, and telomere length regulation. TEL1 is primarily involved in telomere length regulation. By an epistasis analysis, we conclude that Tel1p and the Mre11p/Rad50p/Xrs2p complex function in a single pathway of telomere length regulation.

Duke Scholars

Published In

Genetics

DOI

ISSN

0016-6731

Publication Date

May 2000

Volume

155

Issue

1

Start / End Page

475 / 479

Location

United States

Related Subject Headings

  • Telomere
  • Signal Transduction
  • Saccharomyces cerevisiae Proteins
  • Saccharomyces cerevisiae
  • Protein Serine-Threonine Kinases
  • Intracellular Signaling Peptides and Proteins
  • Fungal Proteins
  • Exodeoxyribonucleases
  • Endodeoxyribonucleases
  • Developmental Biology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Ritchie, K. B., & Petes, T. D. (2000). The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeast. Genetics, 155(1), 475–479. https://doi.org/10.1093/genetics/155.1.475
Ritchie, K. B., and T. D. Petes. “The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeast.Genetics 155, no. 1 (May 2000): 475–79. https://doi.org/10.1093/genetics/155.1.475.
Ritchie, K. B., and T. D. Petes. “The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeast.Genetics, vol. 155, no. 1, May 2000, pp. 475–79. Pubmed, doi:10.1093/genetics/155.1.475.

Published In

Genetics

DOI

ISSN

0016-6731

Publication Date

May 2000

Volume

155

Issue

1

Start / End Page

475 / 479

Location

United States

Related Subject Headings

  • Telomere
  • Signal Transduction
  • Saccharomyces cerevisiae Proteins
  • Saccharomyces cerevisiae
  • Protein Serine-Threonine Kinases
  • Intracellular Signaling Peptides and Proteins
  • Fungal Proteins
  • Exodeoxyribonucleases
  • Endodeoxyribonucleases
  • Developmental Biology