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Analysis of meiotic recombination events near a recombination hotspot in the yeast Saccharomyces cerevisiae.

Publication ,  Journal Article
White, MA; Petes, TD
Published in: Curr Genet
July 1994

The region of yeast chromosome III between the HIS4 and LEU2 genes has an unusually high frequency of meiotic recombination. In order to determine the pattern of cross-over and gene conversion events, we constructed a strain with a number of heterozygous markers in this 25-kb interval. We found that very high levels of recombination are localized to regions of DNA near HIS4. In addition, analysis of the patterns of co-conversion of adjacent markers suggests that there is more than one initiation site contributing to recombination of HIS4.

Duke Scholars

Published In

Curr Genet

DOI

ISSN

0172-8083

Publication Date

July 1994

Volume

26

Issue

1

Start / End Page

21 / 30

Location

United States

Related Subject Headings

  • Saccharomyces cerevisiae
  • Microbiology
  • Meiosis
  • Genetic Markers
  • Genetic Complementation Test
  • Gene Conversion
  • Crossing Over, Genetic
  • Chromosomes, Fungal
  • 3107 Microbiology
  • 3105 Genetics
 

Citation

APA
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ICMJE
MLA
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White, M. A., & Petes, T. D. (1994). Analysis of meiotic recombination events near a recombination hotspot in the yeast Saccharomyces cerevisiae. Curr Genet, 26(1), 21–30. https://doi.org/10.1007/BF00326300
White, M. A., and T. D. Petes. “Analysis of meiotic recombination events near a recombination hotspot in the yeast Saccharomyces cerevisiae.Curr Genet 26, no. 1 (July 1994): 21–30. https://doi.org/10.1007/BF00326300.
White, M. A., and T. D. Petes. “Analysis of meiotic recombination events near a recombination hotspot in the yeast Saccharomyces cerevisiae.Curr Genet, vol. 26, no. 1, July 1994, pp. 21–30. Pubmed, doi:10.1007/BF00326300.
Journal cover image

Published In

Curr Genet

DOI

ISSN

0172-8083

Publication Date

July 1994

Volume

26

Issue

1

Start / End Page

21 / 30

Location

United States

Related Subject Headings

  • Saccharomyces cerevisiae
  • Microbiology
  • Meiosis
  • Genetic Markers
  • Genetic Complementation Test
  • Gene Conversion
  • Crossing Over, Genetic
  • Chromosomes, Fungal
  • 3107 Microbiology
  • 3105 Genetics