A model for slow axonal transport and its application to neurofilamentous neuropathies.
Publication
, Journal Article
Blum, JJ; Reed, MC
Published in: Cell motility and the cytoskeleton
January 1989
A model for slow axonal transport is developed in which the essential features are reversible binding of cytoskeletal elements and of soluble cytosolic proteins to each other and to motile elements such as actin microfilaments. Computer simulation of the equations of the model demonstrate that the model can account for many of the features of the SCa and SCb waves observed in pulse experiments. The model also provides a unified explanation for the increase and decrease of neurofilament transport rates observed in various toxicant-induced neuropathies.
Duke Scholars
Published In
Cell motility and the cytoskeleton
DOI
EISSN
1097-0169
ISSN
0886-1544
Publication Date
January 1989
Volume
12
Issue
1
Start / End Page
53 / 65
Related Subject Headings
- Neurons
- Nervous System Diseases
- Models, Neurological
- Intermediate Filaments
- Humans
- Developmental Biology
- Cytoskeleton
- Cytoskeletal Proteins
- Computer Simulation
- Axons
Citation
APA
Chicago
ICMJE
MLA
NLM
Blum, J. J., & Reed, M. C. (1989). A model for slow axonal transport and its application to neurofilamentous neuropathies. Cell Motility and the Cytoskeleton, 12(1), 53–65. https://doi.org/10.1002/cm.970120107
Blum, J. J., and M. C. Reed. “A model for slow axonal transport and its application to neurofilamentous neuropathies.” Cell Motility and the Cytoskeleton 12, no. 1 (January 1989): 53–65. https://doi.org/10.1002/cm.970120107.
Blum JJ, Reed MC. A model for slow axonal transport and its application to neurofilamentous neuropathies. Cell motility and the cytoskeleton. 1989 Jan;12(1):53–65.
Blum, J. J., and M. C. Reed. “A model for slow axonal transport and its application to neurofilamentous neuropathies.” Cell Motility and the Cytoskeleton, vol. 12, no. 1, Jan. 1989, pp. 53–65. Epmc, doi:10.1002/cm.970120107.
Blum JJ, Reed MC. A model for slow axonal transport and its application to neurofilamentous neuropathies. Cell motility and the cytoskeleton. 1989 Jan;12(1):53–65.
Published In
Cell motility and the cytoskeleton
DOI
EISSN
1097-0169
ISSN
0886-1544
Publication Date
January 1989
Volume
12
Issue
1
Start / End Page
53 / 65
Related Subject Headings
- Neurons
- Nervous System Diseases
- Models, Neurological
- Intermediate Filaments
- Humans
- Developmental Biology
- Cytoskeleton
- Cytoskeletal Proteins
- Computer Simulation
- Axons