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Dual release of VEGF and dexamethasone from microspheres incorporated in anti-fouling hydrogels

Publication ,  Journal Article
Norton, LW; Tegnell, E; Reichert, WM
Published in: Transactions - 7th World Biomaterials Congress
December 1, 2004

The modification of anti-fouling hydrogels to incorporate microspheres for the delivery of vascular endothelial growth factor (VEGF) and dexamethasone was studied. It was observed that the hydrogen release curves exhibited a burst release of the encapsulated drug for VEGF and dexamethasone. The dexamethasone content of the samples was measured using HPLC and the VEGF release was determined using VEGF ELISA. It was stated that the hydrogel-microsphere drug delivery device will be optimized and used as a coating for implanted microdialysis probes for modulating the wound healing response.

Duke Scholars

Published In

Transactions - 7th World Biomaterials Congress

Publication Date

December 1, 2004

Start / End Page

357
 

Citation

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Norton, L. W., Tegnell, E., & Reichert, W. M. (2004). Dual release of VEGF and dexamethasone from microspheres incorporated in anti-fouling hydrogels. Transactions - 7th World Biomaterials Congress, 357.
Norton, L. W., E. Tegnell, and W. M. Reichert. “Dual release of VEGF and dexamethasone from microspheres incorporated in anti-fouling hydrogels.” Transactions - 7th World Biomaterials Congress, December 1, 2004, 357.
Norton LW, Tegnell E, Reichert WM. Dual release of VEGF and dexamethasone from microspheres incorporated in anti-fouling hydrogels. Transactions - 7th World Biomaterials Congress. 2004 Dec 1;357.
Norton, L. W., et al. “Dual release of VEGF and dexamethasone from microspheres incorporated in anti-fouling hydrogels.” Transactions - 7th World Biomaterials Congress, Dec. 2004, p. 357.
Norton LW, Tegnell E, Reichert WM. Dual release of VEGF and dexamethasone from microspheres incorporated in anti-fouling hydrogels. Transactions - 7th World Biomaterials Congress. 2004 Dec 1;357.

Published In

Transactions - 7th World Biomaterials Congress

Publication Date

December 1, 2004

Start / End Page

357