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Anticentromere antibody. Clinical Correlations and association with favorable prognosis in patients with scleroderma variants.

Publication ,  Journal Article
McCarty, GA; Rice, JR; Bembe, ML; Barada, FA
Published in: Arthritis Rheum
January 1983

The presence of antibody to the chromosomal centromere appears to be associated with a subset of patients with the limited CREST form of scleroderma. To further define the prognostic value of this autoantibody, 27 patients, who were identified as having anticentromere antibody by screening antinuclear antibody tests using HEp-2 cell substrates, were followed clinically and serologically for 2 years. The presence of anticentromere antibody is common in the limited CREST forms of systemic sclerosis, and it is often the only autoantibody specificity present in the sera of patients with the CREST variant. When compared with other patients who exhibit speckled or nucleolar antinuclear antibody patterns, those with anticentromere antibody had significantly less major organ system involvement.

Duke Scholars

Published In

Arthritis Rheum

DOI

ISSN

0004-3591

Publication Date

January 1983

Volume

26

Issue

1

Start / End Page

1 / 7

Location

United States

Related Subject Headings

  • Telangiectasis
  • Syndrome
  • Scleroderma, Systemic
  • Raynaud Disease
  • Prognosis
  • Middle Aged
  • Male
  • Humans
  • Follow-Up Studies
  • Fluorescent Antibody Technique
 

Citation

APA
Chicago
ICMJE
MLA
NLM
McCarty, G. A., Rice, J. R., Bembe, M. L., & Barada, F. A. (1983). Anticentromere antibody. Clinical Correlations and association with favorable prognosis in patients with scleroderma variants. Arthritis Rheum, 26(1), 1–7. https://doi.org/10.1002/art.1780260101
McCarty, G. A., J. R. Rice, M. L. Bembe, and F. A. Barada. “Anticentromere antibody. Clinical Correlations and association with favorable prognosis in patients with scleroderma variants.Arthritis Rheum 26, no. 1 (January 1983): 1–7. https://doi.org/10.1002/art.1780260101.
McCarty, G. A., et al. “Anticentromere antibody. Clinical Correlations and association with favorable prognosis in patients with scleroderma variants.Arthritis Rheum, vol. 26, no. 1, Jan. 1983, pp. 1–7. Pubmed, doi:10.1002/art.1780260101.
Journal cover image

Published In

Arthritis Rheum

DOI

ISSN

0004-3591

Publication Date

January 1983

Volume

26

Issue

1

Start / End Page

1 / 7

Location

United States

Related Subject Headings

  • Telangiectasis
  • Syndrome
  • Scleroderma, Systemic
  • Raynaud Disease
  • Prognosis
  • Middle Aged
  • Male
  • Humans
  • Follow-Up Studies
  • Fluorescent Antibody Technique