The role of tregs in glioma-mediated immunosuppression: potential target for intervention.
Publication
, Journal Article
Humphries, W; Wei, J; Sampson, JH; Heimberger, AB
Published in: Neurosurg Clin N Am
January 2010
The role of regulatory T cells (Tregs) in mediating immune suppression of anti-tumor immune responses is increasingly appreciated in patients with malignancies-especially within the malignant glioma patient population. This article discuss the role and prognostic significance of Tregs within glioma patients and delineates potential approaches for their inhibition that can be used alone or in combination with other immune therapeutics in clinical trials and in the clinical settings of recurrent or residual disease.
Duke Scholars
Published In
Neurosurg Clin N Am
DOI
EISSN
1558-1349
Publication Date
January 2010
Volume
21
Issue
1
Start / End Page
125 / 137
Location
United States
Related Subject Headings
- T-Lymphocytes, Regulatory
- Prognosis
- Neurology & Neurosurgery
- Immunotherapy
- Immune Tolerance
- Humans
- Glioma
- Central Nervous System
- Brain Neoplasms
- Animals
Citation
APA
Chicago
ICMJE
MLA
NLM
Humphries, W., Wei, J., Sampson, J. H., & Heimberger, A. B. (2010). The role of tregs in glioma-mediated immunosuppression: potential target for intervention. Neurosurg Clin N Am, 21(1), 125–137. https://doi.org/10.1016/j.nec.2009.08.012
Humphries, William, Jun Wei, John H. Sampson, and Amy B. Heimberger. “The role of tregs in glioma-mediated immunosuppression: potential target for intervention.” Neurosurg Clin N Am 21, no. 1 (January 2010): 125–37. https://doi.org/10.1016/j.nec.2009.08.012.
Humphries W, Wei J, Sampson JH, Heimberger AB. The role of tregs in glioma-mediated immunosuppression: potential target for intervention. Neurosurg Clin N Am. 2010 Jan;21(1):125–37.
Humphries, William, et al. “The role of tregs in glioma-mediated immunosuppression: potential target for intervention.” Neurosurg Clin N Am, vol. 21, no. 1, Jan. 2010, pp. 125–37. Pubmed, doi:10.1016/j.nec.2009.08.012.
Humphries W, Wei J, Sampson JH, Heimberger AB. The role of tregs in glioma-mediated immunosuppression: potential target for intervention. Neurosurg Clin N Am. 2010 Jan;21(1):125–137.
Published In
Neurosurg Clin N Am
DOI
EISSN
1558-1349
Publication Date
January 2010
Volume
21
Issue
1
Start / End Page
125 / 137
Location
United States
Related Subject Headings
- T-Lymphocytes, Regulatory
- Prognosis
- Neurology & Neurosurgery
- Immunotherapy
- Immune Tolerance
- Humans
- Glioma
- Central Nervous System
- Brain Neoplasms
- Animals