Long-term implantation of voltammetric oxidase/peroxide glucose sensors in the rat peritoneum.
Publication
, Journal Article
Clark, LC; Noyes, LK; Spokane, RB; Sudan, R; Miller, ML
Published in: Methods Enzymol
1988
Methods for designing, fabricating, testing in vitro and in vivo, and improving chronically implantable oxidase/peroxide-type polarographic glucose sensors are described. Voltammetric means to evaluate oxygen supply to the sensor and to measure the nearby microcirculation with hydrogen washout techniques using the implanted glucose sensor are outlined. Because some peritoneally implanted sensors have, perhaps surprisingly, remained functional for months, such devices may prove with further development to be useful as the sensing components in artificial pancreatic beta cells for the control of diabetes.
Duke Scholars
Published In
Methods Enzymol
DOI
ISSN
0076-6879
Publication Date
1988
Volume
137
Start / End Page
68 / 89
Location
United States
Related Subject Headings
- Rats, Inbred Strains
- Rats
- Polarography
- Peritoneal Cavity
- Oxygen Consumption
- Indicators and Reagents
- Glucose Oxidase
- Glucose
- Female
- Enzymes, Immobilized
Citation
APA
Chicago
ICMJE
MLA
NLM
Clark, L. C., Noyes, L. K., Spokane, R. B., Sudan, R., & Miller, M. L. (1988). Long-term implantation of voltammetric oxidase/peroxide glucose sensors in the rat peritoneum. Methods Enzymol, 137, 68–89. https://doi.org/10.1016/0076-6879(88)37008-4
Clark, L. C., L. K. Noyes, R. B. Spokane, R. Sudan, and M. L. Miller. “Long-term implantation of voltammetric oxidase/peroxide glucose sensors in the rat peritoneum.” Methods Enzymol 137 (1988): 68–89. https://doi.org/10.1016/0076-6879(88)37008-4.
Clark LC, Noyes LK, Spokane RB, Sudan R, Miller ML. Long-term implantation of voltammetric oxidase/peroxide glucose sensors in the rat peritoneum. Methods Enzymol. 1988;137:68–89.
Clark, L. C., et al. “Long-term implantation of voltammetric oxidase/peroxide glucose sensors in the rat peritoneum.” Methods Enzymol, vol. 137, 1988, pp. 68–89. Pubmed, doi:10.1016/0076-6879(88)37008-4.
Clark LC, Noyes LK, Spokane RB, Sudan R, Miller ML. Long-term implantation of voltammetric oxidase/peroxide glucose sensors in the rat peritoneum. Methods Enzymol. 1988;137:68–89.
Published In
Methods Enzymol
DOI
ISSN
0076-6879
Publication Date
1988
Volume
137
Start / End Page
68 / 89
Location
United States
Related Subject Headings
- Rats, Inbred Strains
- Rats
- Polarography
- Peritoneal Cavity
- Oxygen Consumption
- Indicators and Reagents
- Glucose Oxidase
- Glucose
- Female
- Enzymes, Immobilized