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Pathophysiology and treatment of graft-versus-host disease.

Publication ,  Journal Article
Flowers, ME; Kansu, E; Sullivan, KM
Published in: Hematol Oncol Clin North Am
October 1999

Acute graft-versus-host disease denotes a distinctive syndrome characterized by a triad of dermatitis (rash), hepatitis (jaundice), and gastroenteritis (abdominal pain, diarrhea) developing in the first 100 days after allogeneic hematopoietic cell transplantation. Chronic graft-versus-host disease designates a more diverse syndrome, usually presenting with multiorgan involvement and commonly developing 100 days after hematopoietic cell transplantation. This article discusses the pathophysiology, incidence and predictive factors, clinical manifestations, diagnosis and grading, prevention, and treatment for both types of the disease.

Duke Scholars

Published In

Hematol Oncol Clin North Am

DOI

ISSN

0889-8588

Publication Date

October 1999

Volume

13

Issue

5

Start / End Page

1091 / ix

Location

United States

Related Subject Headings

  • Transplantation
  • Oncology & Carcinogenesis
  • Middle Aged
  • Immunosuppression Therapy
  • Humans
  • Graft vs Host Disease
  • Adult
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Flowers, M. E., Kansu, E., & Sullivan, K. M. (1999). Pathophysiology and treatment of graft-versus-host disease. Hematol Oncol Clin North Am, 13(5), 1091–ix. https://doi.org/10.1016/s0889-8588(05)70111-8
Flowers, M. E., E. Kansu, and K. M. Sullivan. “Pathophysiology and treatment of graft-versus-host disease.Hematol Oncol Clin North Am 13, no. 5 (October 1999): 1091–ix. https://doi.org/10.1016/s0889-8588(05)70111-8.
Flowers ME, Kansu E, Sullivan KM. Pathophysiology and treatment of graft-versus-host disease. Hematol Oncol Clin North Am. 1999 Oct;13(5):1091–ix.
Flowers, M. E., et al. “Pathophysiology and treatment of graft-versus-host disease.Hematol Oncol Clin North Am, vol. 13, no. 5, Oct. 1999, pp. 1091–ix. Pubmed, doi:10.1016/s0889-8588(05)70111-8.
Flowers ME, Kansu E, Sullivan KM. Pathophysiology and treatment of graft-versus-host disease. Hematol Oncol Clin North Am. 1999 Oct;13(5):1091–ix.
Journal cover image

Published In

Hematol Oncol Clin North Am

DOI

ISSN

0889-8588

Publication Date

October 1999

Volume

13

Issue

5

Start / End Page

1091 / ix

Location

United States

Related Subject Headings

  • Transplantation
  • Oncology & Carcinogenesis
  • Middle Aged
  • Immunosuppression Therapy
  • Humans
  • Graft vs Host Disease
  • Adult
  • 3201 Cardiovascular medicine and haematology
  • 1102 Cardiorespiratory Medicine and Haematology