Prenatal dietary choline availability alters postnatal neurotoxic vulnerability in the adult rat.
Publication
, Journal Article
Guo-Ross, SX; Jones, KH; Shetty, AK; Wilson, WA; Swartzwelder, HS
Published in: Neurosci Lett
May 1, 2003
The availability of choline during the prenatal period influences neural and cognitive development. Here we report that choline supplementation during a six-day gestational period protects against neurodegeneration in the posterior cingulate and retrosplenial cortices of adult female rats produced by systemic administration of the N-methyl-D-aspartate receptor antagonist dizocilpine (MK-801). These data show that availability of choline during a brief prenatal period diminishes vulnerability to neurotoxicity in adult offspring.
Duke Scholars
Published In
Neurosci Lett
DOI
ISSN
0304-3940
Publication Date
May 1, 2003
Volume
341
Issue
2
Start / End Page
161 / 163
Location
Ireland
Related Subject Headings
- Rats, Sprague-Dawley
- Rats
- Prenatal Exposure Delayed Effects
- Pregnancy
- Nootropic Agents
- Neurons
- Gyrus Cinguli
- Female
- Excitatory Amino Acid Antagonists
- Dizocilpine Maleate
Citation
APA
Chicago
ICMJE
MLA
NLM
Guo-Ross, S. X., Jones, K. H., Shetty, A. K., Wilson, W. A., & Swartzwelder, H. S. (2003). Prenatal dietary choline availability alters postnatal neurotoxic vulnerability in the adult rat. Neurosci Lett, 341(2), 161–163. https://doi.org/10.1016/s0304-3940(03)00119-8
Guo-Ross, Shirley X., Katherine H. Jones, Ashok K. Shetty, Wilkie A. Wilson, and H Scott Swartzwelder. “Prenatal dietary choline availability alters postnatal neurotoxic vulnerability in the adult rat.” Neurosci Lett 341, no. 2 (May 1, 2003): 161–63. https://doi.org/10.1016/s0304-3940(03)00119-8.
Guo-Ross SX, Jones KH, Shetty AK, Wilson WA, Swartzwelder HS. Prenatal dietary choline availability alters postnatal neurotoxic vulnerability in the adult rat. Neurosci Lett. 2003 May 1;341(2):161–3.
Guo-Ross, Shirley X., et al. “Prenatal dietary choline availability alters postnatal neurotoxic vulnerability in the adult rat.” Neurosci Lett, vol. 341, no. 2, May 2003, pp. 161–63. Pubmed, doi:10.1016/s0304-3940(03)00119-8.
Guo-Ross SX, Jones KH, Shetty AK, Wilson WA, Swartzwelder HS. Prenatal dietary choline availability alters postnatal neurotoxic vulnerability in the adult rat. Neurosci Lett. 2003 May 1;341(2):161–163.
Published In
Neurosci Lett
DOI
ISSN
0304-3940
Publication Date
May 1, 2003
Volume
341
Issue
2
Start / End Page
161 / 163
Location
Ireland
Related Subject Headings
- Rats, Sprague-Dawley
- Rats
- Prenatal Exposure Delayed Effects
- Pregnancy
- Nootropic Agents
- Neurons
- Gyrus Cinguli
- Female
- Excitatory Amino Acid Antagonists
- Dizocilpine Maleate