New insights into Chlamydia intracellular survival mechanisms.
Publication
, Journal Article
Cocchiaro, JL; Valdivia, RH
Published in: Cell Microbiol
November 2009
Chlamydia sp. are responsible for a wide range of diseases of significant clinical and public health importance. In this review, we highlight how recent cellular and functional genomic approaches have significantly increased our knowledge of the pathogenic mechanisms used by these genetically intractable bacteria. As the extensive repertoire of chlamydial proteins that are translocated into the mammalian host is identified and characterized, a molecular understanding of how Chlamydiae co-opt host cellular functions and block innate immune pathways is beginning to emerge.
Duke Scholars
Published In
Cell Microbiol
DOI
EISSN
1462-5822
Publication Date
November 2009
Volume
11
Issue
11
Start / End Page
1571 / 1578
Location
United States
Related Subject Headings
- Virulence Factors
- Models, Biological
- Microbiology
- Microbial Viability
- Immunologic Factors
- Humans
- Host-Pathogen Interactions
- Cytoplasm
- Chlamydia
- Bacterial Proteins
Citation
APA
Chicago
ICMJE
MLA
NLM
Cocchiaro, J. L., & Valdivia, R. H. (2009). New insights into Chlamydia intracellular survival mechanisms. Cell Microbiol, 11(11), 1571–1578. https://doi.org/10.1111/j.1462-5822.2009.01364.x
Published In
Cell Microbiol
DOI
EISSN
1462-5822
Publication Date
November 2009
Volume
11
Issue
11
Start / End Page
1571 / 1578
Location
United States
Related Subject Headings
- Virulence Factors
- Models, Biological
- Microbiology
- Microbial Viability
- Immunologic Factors
- Humans
- Host-Pathogen Interactions
- Cytoplasm
- Chlamydia
- Bacterial Proteins