Skip to main content
Journal cover image

Surface-enhanced Raman gene probes.

Publication ,  Journal Article
Vo-Dinh, T; Houck, K; Stokes, DL
Published in: Analytical chemistry
October 1994

We report for the first time a new type of DNA gene probe based on surface-enhanced Raman scattering (SERS) label detection. The surface-enhanced Raman gene (SERG) probes do not require the use of radioactive labels and have great potential to provide both sensitivity and selectivity. The SERG probe can be used to detect DNA biotargets (e.g., gene sequences, bacteria, viral DNA fragments) via hybridization to DNA sequences complementary to that probe. The analytical figures of merit and its applications in environmental and biomedical areas are discussed.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Analytical chemistry

DOI

EISSN

1520-6882

ISSN

0003-2700

Publication Date

October 1994

Volume

66

Issue

20

Start / End Page

3379 / 3383

Related Subject Headings

  • Spectrum Analysis, Raman
  • Sequence Analysis, DNA
  • Nucleic Acid Hybridization
  • DNA Probes
  • Analytical Chemistry
  • 4004 Chemical engineering
  • 3401 Analytical chemistry
  • 3205 Medical biochemistry and metabolomics
  • 0399 Other Chemical Sciences
  • 0301 Analytical Chemistry
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Vo-Dinh, T., Houck, K., & Stokes, D. L. (1994). Surface-enhanced Raman gene probes. Analytical Chemistry, 66(20), 3379–3383. https://doi.org/10.1021/ac00092a014
Vo-Dinh, T., K. Houck, and D. L. Stokes. “Surface-enhanced Raman gene probes.Analytical Chemistry 66, no. 20 (October 1994): 3379–83. https://doi.org/10.1021/ac00092a014.
Vo-Dinh T, Houck K, Stokes DL. Surface-enhanced Raman gene probes. Analytical chemistry. 1994 Oct;66(20):3379–83.
Vo-Dinh, T., et al. “Surface-enhanced Raman gene probes.Analytical Chemistry, vol. 66, no. 20, Oct. 1994, pp. 3379–83. Epmc, doi:10.1021/ac00092a014.
Vo-Dinh T, Houck K, Stokes DL. Surface-enhanced Raman gene probes. Analytical chemistry. 1994 Oct;66(20):3379–3383.
Journal cover image

Published In

Analytical chemistry

DOI

EISSN

1520-6882

ISSN

0003-2700

Publication Date

October 1994

Volume

66

Issue

20

Start / End Page

3379 / 3383

Related Subject Headings

  • Spectrum Analysis, Raman
  • Sequence Analysis, DNA
  • Nucleic Acid Hybridization
  • DNA Probes
  • Analytical Chemistry
  • 4004 Chemical engineering
  • 3401 Analytical chemistry
  • 3205 Medical biochemistry and metabolomics
  • 0399 Other Chemical Sciences
  • 0301 Analytical Chemistry