Surface-enhanced Raman gene probes.
Publication
, Journal Article
Vo-Dinh, T; Houck, K; Stokes, DL
Published in: Analytical chemistry
October 1994
We report for the first time a new type of DNA gene probe based on surface-enhanced Raman scattering (SERS) label detection. The surface-enhanced Raman gene (SERG) probes do not require the use of radioactive labels and have great potential to provide both sensitivity and selectivity. The SERG probe can be used to detect DNA biotargets (e.g., gene sequences, bacteria, viral DNA fragments) via hybridization to DNA sequences complementary to that probe. The analytical figures of merit and its applications in environmental and biomedical areas are discussed.
Duke Scholars
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Published In
Analytical chemistry
DOI
EISSN
1520-6882
ISSN
0003-2700
Publication Date
October 1994
Volume
66
Issue
20
Start / End Page
3379 / 3383
Related Subject Headings
- Spectrum Analysis, Raman
- Sequence Analysis, DNA
- Nucleic Acid Hybridization
- DNA Probes
- Analytical Chemistry
- 4004 Chemical engineering
- 3401 Analytical chemistry
- 3205 Medical biochemistry and metabolomics
- 0399 Other Chemical Sciences
- 0301 Analytical Chemistry
Citation
APA
Chicago
ICMJE
MLA
NLM
Vo-Dinh, T., Houck, K., & Stokes, D. L. (1994). Surface-enhanced Raman gene probes. Analytical Chemistry, 66(20), 3379–3383. https://doi.org/10.1021/ac00092a014
Vo-Dinh, T., K. Houck, and D. L. Stokes. “Surface-enhanced Raman gene probes.” Analytical Chemistry 66, no. 20 (October 1994): 3379–83. https://doi.org/10.1021/ac00092a014.
Vo-Dinh T, Houck K, Stokes DL. Surface-enhanced Raman gene probes. Analytical chemistry. 1994 Oct;66(20):3379–83.
Vo-Dinh, T., et al. “Surface-enhanced Raman gene probes.” Analytical Chemistry, vol. 66, no. 20, Oct. 1994, pp. 3379–83. Epmc, doi:10.1021/ac00092a014.
Vo-Dinh T, Houck K, Stokes DL. Surface-enhanced Raman gene probes. Analytical chemistry. 1994 Oct;66(20):3379–3383.
Published In
Analytical chemistry
DOI
EISSN
1520-6882
ISSN
0003-2700
Publication Date
October 1994
Volume
66
Issue
20
Start / End Page
3379 / 3383
Related Subject Headings
- Spectrum Analysis, Raman
- Sequence Analysis, DNA
- Nucleic Acid Hybridization
- DNA Probes
- Analytical Chemistry
- 4004 Chemical engineering
- 3401 Analytical chemistry
- 3205 Medical biochemistry and metabolomics
- 0399 Other Chemical Sciences
- 0301 Analytical Chemistry