Combined modality treatment for rectal cancer.
Publication
, Journal Article
Zhu, AX; Willett, CG
Published in: Semin Oncol
February 2005
Significant gains have been achieved in the integration of radiation therapy (RT) and chemotherapy with surgery in the management of patients with localized rectal cancer. Treatment combinations of RT and chemotherapy with surgery have evolved to neoadjuvant approaches of these modalities to enhance sphincter preservation, tumor control, and reduction of acute and late treatment-related morbidity. Although 5-fluorouracil (5-FU)-based chemotherapy in combination with RT remains the standard adjuvant therapy for rectal cancer, the integration of novel chemotherapeutic agents and biologic modulators is being actively investigated.
Duke Scholars
Published In
Semin Oncol
DOI
ISSN
0093-7754
Publication Date
February 2005
Volume
32
Issue
1
Start / End Page
103 / 112
Location
United States
Related Subject Headings
- Transforming Growth Factor alpha
- Rectal Neoplasms
- Radiotherapy, Adjuvant
- Oxaliplatin
- Organoplatinum Compounds
- Oncology & Carcinogenesis
- Irinotecan
- Humans
- Fluorouracil
- Deoxycytidine
Citation
APA
Chicago
ICMJE
MLA
NLM
Zhu, A. X., & Willett, C. G. (2005). Combined modality treatment for rectal cancer. Semin Oncol, 32(1), 103–112. https://doi.org/10.1053/j.seminoncol.2004.09.032
Zhu, Andrew X., and Christopher G. Willett. “Combined modality treatment for rectal cancer.” Semin Oncol 32, no. 1 (February 2005): 103–12. https://doi.org/10.1053/j.seminoncol.2004.09.032.
Zhu AX, Willett CG. Combined modality treatment for rectal cancer. Semin Oncol. 2005 Feb;32(1):103–12.
Zhu, Andrew X., and Christopher G. Willett. “Combined modality treatment for rectal cancer.” Semin Oncol, vol. 32, no. 1, Feb. 2005, pp. 103–12. Pubmed, doi:10.1053/j.seminoncol.2004.09.032.
Zhu AX, Willett CG. Combined modality treatment for rectal cancer. Semin Oncol. 2005 Feb;32(1):103–112.
Published In
Semin Oncol
DOI
ISSN
0093-7754
Publication Date
February 2005
Volume
32
Issue
1
Start / End Page
103 / 112
Location
United States
Related Subject Headings
- Transforming Growth Factor alpha
- Rectal Neoplasms
- Radiotherapy, Adjuvant
- Oxaliplatin
- Organoplatinum Compounds
- Oncology & Carcinogenesis
- Irinotecan
- Humans
- Fluorouracil
- Deoxycytidine