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Prevalence of human African trypanosomiasis in the Democratic Republic of the Congo.

Publication ,  Journal Article
Mumba, D; Bohorquez, E; Messina, J; Kande, V; Taylor, SM; Tshefu, AK; Muwonga, J; Kashamuka, MM; Emch, M; Tidwell, R; Büscher, P; Meshnick, SR
Published in: PLoS Negl Trop Dis
August 2011

Human African Trypanosomiasis (HAT) is a major public health problem in the Democratic Republic of the Congo (DRC). Active and passive surveillance for HAT is conducted but may underestimate the true prevalence of the disease. We used ELISA to screen 7,769 leftover dried blood spots from a nationally representative population-based survey, the 2007 Demographic and Health Survey. 26 samples were positive by ELISA. Three of these were also positive by trypanolysis and/or PCR. From these data, we estimate that there were 18,592 people with HAT (95% confidence interval, 4,883-32,302) in the DRC in 2007, slightly more than twice as many as were reported.

Duke Scholars

Published In

PLoS Negl Trop Dis

DOI

EISSN

1935-2735

Publication Date

August 2011

Volume

5

Issue

8

Start / End Page

e1246

Location

United States

Related Subject Headings

  • Trypanosomiasis, African
  • Tropical Medicine
  • Prevalence
  • Population Surveillance
  • Middle Aged
  • Male
  • Humans
  • Health Surveys
  • Female
  • Enzyme-Linked Immunosorbent Assay
 

Citation

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ICMJE
MLA
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Mumba, D., Bohorquez, E., Messina, J., Kande, V., Taylor, S. M., Tshefu, A. K., … Meshnick, S. R. (2011). Prevalence of human African trypanosomiasis in the Democratic Republic of the Congo. PLoS Negl Trop Dis, 5(8), e1246. https://doi.org/10.1371/journal.pntd.0001246

Published In

PLoS Negl Trop Dis

DOI

EISSN

1935-2735

Publication Date

August 2011

Volume

5

Issue

8

Start / End Page

e1246

Location

United States

Related Subject Headings

  • Trypanosomiasis, African
  • Tropical Medicine
  • Prevalence
  • Population Surveillance
  • Middle Aged
  • Male
  • Humans
  • Health Surveys
  • Female
  • Enzyme-Linked Immunosorbent Assay