Skip to main content
Journal cover image

Aggravation of exercise performance in patients with anemia by 3% carboxyhemoglobin.

Publication ,  Journal Article
Aronow, WS; Schlueter, WJ; Williams, MA; Petratis, M; Sketch, MH
Published in: Environ Res
December 1984

To evaluate the effect of breathing 50 ppm carbon monoxide (CO) on exercise capacity in persons with anemia, 10 nonsmoking subjects with chronic anemia (mean hemoglobin 8.9 g%) were studied. No subject had heart or lung disease. By double-blind, randomized, crossover design, duration of fatigue-limited exercise after breathing CO and purified air for 1 hr was compared. Mean carboxyhemoglobin levels increased from 2.14 to 3.38% after breathing CO and decreased from 2.15 to 1.86% after breathing purified air, P less than 0.004. Mean exercise duration decreased from 270.8 to 221.0 sec after breathing CO in contrast to an increase from 267.9 to 271.6 sec after breathing purified air, P less than 0.0001. Hence, in the absence of clinical heart or lung disease, increasing carboxyhemoglobin concentrations aggravate exercise performance in nonsmokers with chronic anemia.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Environ Res

DOI

ISSN

0013-9351

Publication Date

December 1984

Volume

35

Issue

2

Start / End Page

394 / 398

Location

Netherlands

Related Subject Headings

  • Toxicology
  • Rest
  • Random Allocation
  • Physical Exertion
  • Middle Aged
  • Male
  • Humans
  • Heart Rate
  • Female
  • Double-Blind Method
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Aronow, W. S., Schlueter, W. J., Williams, M. A., Petratis, M., & Sketch, M. H. (1984). Aggravation of exercise performance in patients with anemia by 3% carboxyhemoglobin. Environ Res, 35(2), 394–398. https://doi.org/10.1016/0013-9351(84)90145-2
Aronow, W. S., W. J. Schlueter, M. A. Williams, M. Petratis, and M. H. Sketch. “Aggravation of exercise performance in patients with anemia by 3% carboxyhemoglobin.Environ Res 35, no. 2 (December 1984): 394–98. https://doi.org/10.1016/0013-9351(84)90145-2.
Aronow WS, Schlueter WJ, Williams MA, Petratis M, Sketch MH. Aggravation of exercise performance in patients with anemia by 3% carboxyhemoglobin. Environ Res. 1984 Dec;35(2):394–8.
Aronow, W. S., et al. “Aggravation of exercise performance in patients with anemia by 3% carboxyhemoglobin.Environ Res, vol. 35, no. 2, Dec. 1984, pp. 394–98. Pubmed, doi:10.1016/0013-9351(84)90145-2.
Aronow WS, Schlueter WJ, Williams MA, Petratis M, Sketch MH. Aggravation of exercise performance in patients with anemia by 3% carboxyhemoglobin. Environ Res. 1984 Dec;35(2):394–398.
Journal cover image

Published In

Environ Res

DOI

ISSN

0013-9351

Publication Date

December 1984

Volume

35

Issue

2

Start / End Page

394 / 398

Location

Netherlands

Related Subject Headings

  • Toxicology
  • Rest
  • Random Allocation
  • Physical Exertion
  • Middle Aged
  • Male
  • Humans
  • Heart Rate
  • Female
  • Double-Blind Method