Monocyte chemotactic mechanisms in patients with hypernephroma.
Publication
, Journal Article
Hemstreet, GP; Snyderman, R
Published in: Natl Cancer Inst Monogr
December 1978
Peripheral blood monocyte chemotaxis was evaluated in 15 patients with hypernephroma, 10 of whom were evaluated preoperatively and postoperatively. Five patients had a significantly reduced response preoperatively that returned to normal levels after radical nephrectomy. Animal experiments confirm the presence of a low-molecular weight (6,000--10,000 daltons) inhibitor, which is heat labile and functions at the macrophage level. Preliminary experiments indicate inhibitors of macrophage chemotaxis can be extracted from renal cell carcinomas. The importance of these inhibitors in modulating immune surveillance is discussed.
Duke Scholars
Published In
Natl Cancer Inst Monogr
ISSN
0083-1921
Publication Date
December 1978
Issue
49
Start / End Page
115 / 118
Location
United States
Related Subject Headings
- Time Factors
- Neoplasms, Experimental
- Monocytes
- Mice
- Male
- Lymphocytes
- Lymphocyte Activation
- Kidney Neoplasms
- In Vitro Techniques
- Humans
Citation
APA
Chicago
ICMJE
MLA
NLM
Hemstreet, G. P., & Snyderman, R. (1978). Monocyte chemotactic mechanisms in patients with hypernephroma. Natl Cancer Inst Monogr, (49), 115–118.
Hemstreet, G. P., and R. Snyderman. “Monocyte chemotactic mechanisms in patients with hypernephroma.” Natl Cancer Inst Monogr, no. 49 (December 1978): 115–18.
Hemstreet GP, Snyderman R. Monocyte chemotactic mechanisms in patients with hypernephroma. Natl Cancer Inst Monogr. 1978 Dec;(49):115–8.
Hemstreet, G. P., and R. Snyderman. “Monocyte chemotactic mechanisms in patients with hypernephroma.” Natl Cancer Inst Monogr, no. 49, Dec. 1978, pp. 115–18.
Hemstreet GP, Snyderman R. Monocyte chemotactic mechanisms in patients with hypernephroma. Natl Cancer Inst Monogr. 1978 Dec;(49):115–118.
Published In
Natl Cancer Inst Monogr
ISSN
0083-1921
Publication Date
December 1978
Issue
49
Start / End Page
115 / 118
Location
United States
Related Subject Headings
- Time Factors
- Neoplasms, Experimental
- Monocytes
- Mice
- Male
- Lymphocytes
- Lymphocyte Activation
- Kidney Neoplasms
- In Vitro Techniques
- Humans