Duloxetine treatment for relapse prevention in adults with generalized anxiety disorder: a double-blind placebo-controlled trial.
Publication
, Journal Article
Davidson, JRT; Wittchen, H-U; Llorca, P-M; Erickson, J; Detke, M; Ball, SG; Russell, JM
Published in: Eur Neuropsychopharmacol
September 2008
The objective was to examine duloxetine 60-120 mg/day treatment for relapse prevention in adults with generalized anxiety disorder (GAD). Adult patients (N=887; mean age=43.3 years; 61.0% female) with DSM-IV-TR-defined GAD diagnosis were treated with duloxetine for 26 weeks. Patients who completed open-label phase and were treatment responders (>or=50% reduction in Hamilton Anxiety Rating Scale total score to or=2-point increase in illness severity ratings or by discontinuation due to lack of efficacy. During the double-blind phase, placebo-treated patients (N=201) relapsed more frequently (41.8%) than duloxetine-treated patients (13.7%, N=204, P
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Published In
Eur Neuropsychopharmacol
DOI
ISSN
0924-977X
Publication Date
September 2008
Volume
18
Issue
9
Start / End Page
673 / 681
Location
Netherlands
Related Subject Headings
- Time Factors
- Thiophenes
- Secondary Prevention
- Retrospective Studies
- Psychiatry
- Psychiatric Status Rating Scales
- Middle Aged
- Male
- Humans
- Female
Citation
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Chicago
ICMJE
MLA
NLM
Davidson, J. R. T., Wittchen, H.-U., Llorca, P.-M., Erickson, J., Detke, M., Ball, S. G., & Russell, J. M. (2008). Duloxetine treatment for relapse prevention in adults with generalized anxiety disorder: a double-blind placebo-controlled trial. Eur Neuropsychopharmacol, 18(9), 673–681. https://doi.org/10.1016/j.euroneuro.2008.05.002
Davidson, Jonathan R. T., Hans-Ulrich Wittchen, Pierre-Michel Llorca, Janelle Erickson, Michael Detke, Susan G. Ball, and James M. Russell. “Duloxetine treatment for relapse prevention in adults with generalized anxiety disorder: a double-blind placebo-controlled trial.” Eur Neuropsychopharmacol 18, no. 9 (September 2008): 673–81. https://doi.org/10.1016/j.euroneuro.2008.05.002.
Davidson JRT, Wittchen H-U, Llorca P-M, Erickson J, Detke M, Ball SG, et al. Duloxetine treatment for relapse prevention in adults with generalized anxiety disorder: a double-blind placebo-controlled trial. Eur Neuropsychopharmacol. 2008 Sep;18(9):673–81.
Davidson, Jonathan R. T., et al. “Duloxetine treatment for relapse prevention in adults with generalized anxiety disorder: a double-blind placebo-controlled trial.” Eur Neuropsychopharmacol, vol. 18, no. 9, Sept. 2008, pp. 673–81. Pubmed, doi:10.1016/j.euroneuro.2008.05.002.
Davidson JRT, Wittchen H-U, Llorca P-M, Erickson J, Detke M, Ball SG, Russell JM. Duloxetine treatment for relapse prevention in adults with generalized anxiety disorder: a double-blind placebo-controlled trial. Eur Neuropsychopharmacol. 2008 Sep;18(9):673–681.
Published In
Eur Neuropsychopharmacol
DOI
ISSN
0924-977X
Publication Date
September 2008
Volume
18
Issue
9
Start / End Page
673 / 681
Location
Netherlands
Related Subject Headings
- Time Factors
- Thiophenes
- Secondary Prevention
- Retrospective Studies
- Psychiatry
- Psychiatric Status Rating Scales
- Middle Aged
- Male
- Humans
- Female