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Treatment of depression in the medically ill.

Publication ,  Journal Article
Krishnan, KRR
Published in: J Clin Psychopharmacol
August 2005

Most studies on treatment methods in elderly depressive patients have included primarily patients in good physical health, excluding medical comorbidity, despite the fact that depression with medical comorbidity is the norm rather than the exception. In addition, depression is known to increase disability and mortality among the medically ill. This, therefore, becomes an extremely important issue. Although data are limited, the available evidence suggests that depression concomitant with medical illness can be treated. One or more of the selective serotonin reuptake inhibitors have demonstrated potential usefulness in depressed patients with ischemic heart disease, diabetes, dementia, and Parkinson's disease and in patients after stroke and after myocardial infarction. Large-scale trials are needed to assess not only the safety and effectiveness of agents for the treatment of depression in comorbid illness, but also the effects of depression on the course of the medical illness itself.

Duke Scholars

Published In

J Clin Psychopharmacol

DOI

ISSN

0271-0749

Publication Date

August 2005

Volume

25

Issue

4 Suppl 1

Start / End Page

S14 / S18

Location

United States

Related Subject Headings

  • Stroke
  • Psychiatry
  • Parkinson Disease
  • Humans
  • Diabetes Mellitus
  • Depressive Disorder
  • Dementia
  • Coronary Artery Disease
  • Cognitive Behavioral Therapy
  • Antidepressive Agents
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Krishnan, K. R. R. (2005). Treatment of depression in the medically ill. J Clin Psychopharmacol, 25(4 Suppl 1), S14–S18. https://doi.org/10.1097/01.jcp.0000162808.92194.2a
Krishnan, K Ranga Rama. “Treatment of depression in the medically ill.J Clin Psychopharmacol 25, no. 4 Suppl 1 (August 2005): S14–18. https://doi.org/10.1097/01.jcp.0000162808.92194.2a.
Krishnan KRR. Treatment of depression in the medically ill. J Clin Psychopharmacol. 2005 Aug;25(4 Suppl 1):S14–8.
Krishnan, K. Ranga Rama. “Treatment of depression in the medically ill.J Clin Psychopharmacol, vol. 25, no. 4 Suppl 1, Aug. 2005, pp. S14–18. Pubmed, doi:10.1097/01.jcp.0000162808.92194.2a.
Krishnan KRR. Treatment of depression in the medically ill. J Clin Psychopharmacol. 2005 Aug;25(4 Suppl 1):S14–S18.

Published In

J Clin Psychopharmacol

DOI

ISSN

0271-0749

Publication Date

August 2005

Volume

25

Issue

4 Suppl 1

Start / End Page

S14 / S18

Location

United States

Related Subject Headings

  • Stroke
  • Psychiatry
  • Parkinson Disease
  • Humans
  • Diabetes Mellitus
  • Depressive Disorder
  • Dementia
  • Coronary Artery Disease
  • Cognitive Behavioral Therapy
  • Antidepressive Agents