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An efficient synthesis of fluorinated azaheterocycles by aminocyclization of alkenes.
Publication
, Journal Article
Huang, H-T; Lacy, TC; Błachut, B; Ortiz, GX; Wang, Q
Published in: Organic letters
April 2013
A general and efficient approach to important fluorinated azaheterocycles has been developed by incorporating nucleophilic fluorination into alkene difunctionalization. This intramolecular aminofluorination transformation of alkenes has been achieved via the aminocyclization of reactive unsaturated N-iodoamines, which can be generated in situ from either unsaturated N-chloramines or their amine precursors in a one-pot protocol.
Duke Scholars
Published In
Organic letters
DOI
EISSN
1523-7052
ISSN
1523-7060
Publication Date
April 2013
Volume
15
Issue
8
Start / End Page
1818 / 1821
Related Subject Headings
- Stereoisomerism
- Organic Chemistry
- Molecular Structure
- Hydrocarbons, Fluorinated
- Cyclization
- Catalysis
- Aza Compounds
- Amines
- Alkenes
- 34 Chemical sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Huang, H.-T., Lacy, T. C., Błachut, B., Ortiz, G. X., & Wang, Q. (2013). An efficient synthesis of fluorinated azaheterocycles by aminocyclization of alkenes. Organic Letters, 15(8), 1818–1821. https://doi.org/10.1021/ol4003866
Huang, Hai-Tsang, Tyler C. Lacy, Barbara Błachut, Gerardo X. Ortiz, and Qiu Wang. “An efficient synthesis of fluorinated azaheterocycles by aminocyclization of alkenes.” Organic Letters 15, no. 8 (April 2013): 1818–21. https://doi.org/10.1021/ol4003866.
Huang H-T, Lacy TC, Błachut B, Ortiz GX, Wang Q. An efficient synthesis of fluorinated azaheterocycles by aminocyclization of alkenes. Organic letters. 2013 Apr;15(8):1818–21.
Huang, Hai-Tsang, et al. “An efficient synthesis of fluorinated azaheterocycles by aminocyclization of alkenes.” Organic Letters, vol. 15, no. 8, Apr. 2013, pp. 1818–21. Epmc, doi:10.1021/ol4003866.
Huang H-T, Lacy TC, Błachut B, Ortiz GX, Wang Q. An efficient synthesis of fluorinated azaheterocycles by aminocyclization of alkenes. Organic letters. 2013 Apr;15(8):1818–1821.
![Journal cover image](https://secure.syndetics.com/index.aspx?isbn=/lc.gif&issn=1523-7052&client=dukeuniv)
Published In
Organic letters
DOI
EISSN
1523-7052
ISSN
1523-7060
Publication Date
April 2013
Volume
15
Issue
8
Start / End Page
1818 / 1821
Related Subject Headings
- Stereoisomerism
- Organic Chemistry
- Molecular Structure
- Hydrocarbons, Fluorinated
- Cyclization
- Catalysis
- Aza Compounds
- Amines
- Alkenes
- 34 Chemical sciences