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Radiologic correlates of antidepressant-induced delirium: the possible significance of basal-ganglia lesions.

Publication ,  Journal Article
Figiel, GS; Krishnan, KR; Breitner, JC; Nemeroff, CB
Published in: J Neuropsychiatry Clin Neurosci
1989

Antidepressant-induced delirium in five of 60 (8%) patients over the age of 45 is reported. In each case, delirium developed within two weeks of beginning the antidepressant and appeared to be completely reversible once the medication was discontinued. Brain magnetic resonance imaging revealed basal-ganglia lesions in each patient who developed delirium. This finding indicates that patients with basal-ganglia lesions may be more vulnerable to antidepressant-induced delirium and is consistent with recent data from the neurologic and psychiatric literature that implicate the basal ganglia in the development of other types of delirium.

Duke Scholars

Published In

J Neuropsychiatry Clin Neurosci

DOI

ISSN

0895-0172

Publication Date

1989

Volume

1

Issue

2

Start / End Page

188 / 190

Location

United States

Related Subject Headings

  • Trazodone
  • Risk Factors
  • Psychiatry
  • Nortriptyline
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Fluoxetine
  • Female
 

Citation

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Figiel, G. S., Krishnan, K. R., Breitner, J. C., & Nemeroff, C. B. (1989). Radiologic correlates of antidepressant-induced delirium: the possible significance of basal-ganglia lesions. J Neuropsychiatry Clin Neurosci, 1(2), 188–190. https://doi.org/10.1176/jnp.1.2.188
Figiel, G. S., K. R. Krishnan, J. C. Breitner, and C. B. Nemeroff. “Radiologic correlates of antidepressant-induced delirium: the possible significance of basal-ganglia lesions.J Neuropsychiatry Clin Neurosci 1, no. 2 (1989): 188–90. https://doi.org/10.1176/jnp.1.2.188.
Figiel GS, Krishnan KR, Breitner JC, Nemeroff CB. Radiologic correlates of antidepressant-induced delirium: the possible significance of basal-ganglia lesions. J Neuropsychiatry Clin Neurosci. 1989;1(2):188–90.
Figiel, G. S., et al. “Radiologic correlates of antidepressant-induced delirium: the possible significance of basal-ganglia lesions.J Neuropsychiatry Clin Neurosci, vol. 1, no. 2, 1989, pp. 188–90. Pubmed, doi:10.1176/jnp.1.2.188.
Figiel GS, Krishnan KR, Breitner JC, Nemeroff CB. Radiologic correlates of antidepressant-induced delirium: the possible significance of basal-ganglia lesions. J Neuropsychiatry Clin Neurosci. 1989;1(2):188–190.
Journal cover image

Published In

J Neuropsychiatry Clin Neurosci

DOI

ISSN

0895-0172

Publication Date

1989

Volume

1

Issue

2

Start / End Page

188 / 190

Location

United States

Related Subject Headings

  • Trazodone
  • Risk Factors
  • Psychiatry
  • Nortriptyline
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Fluoxetine
  • Female