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Gastric cancer, version 2.2013: featured updates to the NCCN Guidelines.

Publication ,  Journal Article
Ajani, JA; Bentrem, DJ; Besh, S; D'Amico, TA; Das, P; Denlinger, C; Fakih, MG; Fuchs, CS; Gerdes, H; Glasgow, RE; Hayman, JA; Hofstetter, WL ...
Published in: J Natl Compr Canc Netw
May 1, 2013
Published version (DOI) Link to item

The NCCN Clinical Practice Guidelines in Oncology for Gastric Cancer provide evidence- and consensus-based recommendations for a multidisciplinary approach for the management of patients with gastric cancer. For patients with resectable locoregional cancer, the guidelines recommend gastrectomy with a D1+ or a modified D2 lymph node dissection (performed by experienced surgeons in high-volume centers). Postoperative chemoradiation is the preferred option after complete gastric resection for patients with T3-T4 tumors and node-positive T1-T2 tumors. Postoperative chemotherapy is included as an option after a modified D2 lymph node dissection for this group of patients. Trastuzumab with chemotherapy is recommended as first-line therapy for patients with HER2-positive advanced or metastatic cancer, confirmed by immunohistochemistry and, if needed, by fluorescence in situ hybridization for IHC 2+.

Duke Scholars

Christopher G. Willett
Author Christopher G. Willett Radiation Oncology

Published In

J Natl Compr Canc Netw

DOI

10.6004/jnccn.2013.0070

EISSN

1540-1413

Publication Date

May 1, 2013

Volume

11

Issue

5

Start / End Page

531 / 546

Location

United States

Related Subject Headings

  • Stomach Neoplasms
  • Receptor, erbB-2
  • Receptor, ErbB-2
  • Oncology & Carcinogenesis
  • Neoplasm Staging
  • Lymph Node Excision
  • Humans
  • Gastrectomy
  • Combined Modality Therapy
  • 4203 Health services and systems
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Ajani, J. A., Bentrem, D. J., Besh, S., D’Amico, T. A., Das, P., Denlinger, C., … National Comprehensive Cancer Network. (2013). Gastric cancer, version 2.2013: featured updates to the NCCN Guidelines. J Natl Compr Canc Netw, 11(5), 531–546. https://doi.org/10.6004/jnccn.2013.0070
Ajani, Jaffer A., David J. Bentrem, Stephen Besh, Thomas A. D’Amico, Prajnan Das, Crystal Denlinger, Marwan G. Fakih, et al. “Gastric cancer, version 2.2013: featured updates to the NCCN Guidelines.” J Natl Compr Canc Netw 11, no. 5 (May 1, 2013): 531–46. https://doi.org/10.6004/jnccn.2013.0070.
Ajani JA, Bentrem DJ, Besh S, D’Amico TA, Das P, Denlinger C, et al. Gastric cancer, version 2.2013: featured updates to the NCCN Guidelines. J Natl Compr Canc Netw. 2013 May 1;11(5):531–46.
Ajani, Jaffer A., et al. “Gastric cancer, version 2.2013: featured updates to the NCCN Guidelines.” J Natl Compr Canc Netw, vol. 11, no. 5, May 2013, pp. 531–46. Pubmed, doi:10.6004/jnccn.2013.0070.
Ajani JA, Bentrem DJ, Besh S, D’Amico TA, Das P, Denlinger C, Fakih MG, Fuchs CS, Gerdes H, Glasgow RE, Hayman JA, Hofstetter WL, Ilson DH, Keswani RN, Kleinberg LR, Korn WM, Lockhart AC, Meredith K, Mulcahy MF, Orringer MB, Posey JA, Sasson AR, Scott WJ, Strong VE, Varghese TK, Warren G, Washington MK, Willett C, Wright CD, McMillian NR, Sundar H, National Comprehensive Cancer Network. Gastric cancer, version 2.2013: featured updates to the NCCN Guidelines. J Natl Compr Canc Netw. 2013 May 1;11(5):531–546.

Published In

J Natl Compr Canc Netw

DOI

10.6004/jnccn.2013.0070

EISSN

1540-1413

Publication Date

May 1, 2013

Volume

11

Issue

5

Start / End Page

531 / 546

Location

United States

Related Subject Headings

  • Stomach Neoplasms
  • Receptor, erbB-2
  • Receptor, ErbB-2
  • Oncology & Carcinogenesis
  • Neoplasm Staging
  • Lymph Node Excision
  • Humans
  • Gastrectomy
  • Combined Modality Therapy
  • 4203 Health services and systems