A novel bispecific antibody recruits T cells to eradicate tumors in the "immunologically privileged" central nervous system.
Publication
, Journal Article
Choi, BD; Pastan, I; Bigner, DD; Sampson, JH
Published in: Oncoimmunology
April 1, 2013
Bispecific T-cell engagers (BiTEs) may break multiple barriers that currently limit the use of immunotherapy in glioblastoma patients. We have recently described a novel BiTE specific for a mutated form of the epidermal growth factor receptor, EGFRvIII, that exerts potent antineoplastic effects against established invasive tumors of the brain.
Duke Scholars
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Published In
Oncoimmunology
DOI
ISSN
2162-4011
Publication Date
April 1, 2013
Volume
2
Issue
4
Start / End Page
e23639
Location
United States
Related Subject Headings
- 3211 Oncology and carcinogenesis
- 3204 Immunology
- 1112 Oncology and Carcinogenesis
- 1107 Immunology
Citation
APA
Chicago
ICMJE
MLA
NLM
Choi, B. D., Pastan, I., Bigner, D. D., & Sampson, J. H. (2013). A novel bispecific antibody recruits T cells to eradicate tumors in the "immunologically privileged" central nervous system. Oncoimmunology, 2(4), e23639. https://doi.org/10.4161/onci.23639
Choi, Bryan D., Ira Pastan, Darell D. Bigner, and John H. Sampson. “A novel bispecific antibody recruits T cells to eradicate tumors in the "immunologically privileged" central nervous system.” Oncoimmunology 2, no. 4 (April 1, 2013): e23639. https://doi.org/10.4161/onci.23639.
Choi BD, Pastan I, Bigner DD, Sampson JH. A novel bispecific antibody recruits T cells to eradicate tumors in the "immunologically privileged" central nervous system. Oncoimmunology. 2013 Apr 1;2(4):e23639.
Choi, Bryan D., et al. “A novel bispecific antibody recruits T cells to eradicate tumors in the "immunologically privileged" central nervous system.” Oncoimmunology, vol. 2, no. 4, Apr. 2013, p. e23639. Pubmed, doi:10.4161/onci.23639.
Choi BD, Pastan I, Bigner DD, Sampson JH. A novel bispecific antibody recruits T cells to eradicate tumors in the "immunologically privileged" central nervous system. Oncoimmunology. 2013 Apr 1;2(4):e23639.
Published In
Oncoimmunology
DOI
ISSN
2162-4011
Publication Date
April 1, 2013
Volume
2
Issue
4
Start / End Page
e23639
Location
United States
Related Subject Headings
- 3211 Oncology and carcinogenesis
- 3204 Immunology
- 1112 Oncology and Carcinogenesis
- 1107 Immunology