Overview
- Our QIAL lab advances quantitative imaging by designing novel CT systems, reconstruction algorithms, image analysis and applications, with a core strength in preclinical CT.
- Current efforts center on spectral CT (dual-energy and photon-counting) with nanoparticle contrast agents for theranostics, multidimensional CT for challenging applications such as intracranial aneurysm, cardiac, and perfusion imaging, and modern reconstruction and image processing ( including deep learning).
- In parallel, we lead co-clinical cancer imaging work; I served as PI of the U24 Duke Preclinical Research Resources for Quantitative Imaging Biomarkers within the NCI Co-Clinical Imaging Research Program (CIRP).
- We are also building a virtual preclinical photon-counting CT platform for cancer studies to accelerate method development and translation.
Current Appointments & Affiliations
Professor in Radiology
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2021 - Present
Radiology,
Clinical Science Departments
Research Professor of Biomedical Engineering
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2023 - Present
Biomedical Engineering,
Pratt School of Engineering
Member of the Duke Cancer Institute
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2012 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Supplementary figure FS3 from Neoadjuvant Radiation Therapy and Surgery Improves Metastasis-Free Survival over Surgery Alone in a Primary Mouse Model of Soft Tissue Sarcoma
Other · November 27, 2025 <p>Long-term survival of an autochthonous p53/MCA mouse model in immunocompetent 129/SvJae wild-type mice induced by CRISPR/Cas9</p> ... Full text CiteSupplementary figure FS1 from Neoadjuvant Radiation Therapy and Surgery Improves Metastasis-Free Survival over Surgery Alone in a Primary Mouse Model of Soft Tissue Sarcoma
Other · November 27, 2025 <p>SU2C-SARC032 clinical trial study design</p> ... Full text CiteSupplementary table TS1 from Neoadjuvant Radiation Therapy and Surgery Improves Metastasis-Free Survival over Surgery Alone in a Primary Mouse Model of Soft Tissue Sarcoma
Other · November 27, 2025 <p>Supplementary table 1</p> ... Full text CiteRecent Grants
Development of a Virtual Preclinical CT Platform for Advanced Imaging and Theranostics in Head and Neck Cancer Research
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2025 - 2029Detecting Growth of Intracranial Aneurysms Using Non-Invasive Photon Counting CT in a Murine Model.
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2025 - 2029Cardiac photon counting CT and its application in studying interactions between Alzheimer's and heart disease
ResearchPrincipal Investigator · Awarded by National Institute on Aging · 2021 - 2026View All Grants