Overview
Shelby D. Reed, PhD, is Professor in the Departments of Population Health Sciences and Medicine at Duke University’s School of Medicine. She is the director of the Center for Informing Health Decisions and Therapeutic Area leader for Population Health Sciences at the Duke Clinical Research Institute (DCRI). She also is core faculty at the Duke-Margolis Center for Health Policy. Dr. Reed has over 20 years of experience leading multidisciplinary health outcomes research studies. Dr. Reed has extensive expertise in designing and conducting trial-based and model-based cost-effectiveness analyses of diagnostics, drugs and patient-centered interventions. In 2016, she co-founded the Preference Evaluation Research (PrefER) Group at the DCRI, and she currently serves as its director. She and the group are frequently sought to conduct stated-preference studies to inform regulatory decisions, health policy, care delivery, value assessment and clinical decision making with applied projects spanning a wide range of therapeutic areas. She served as President for ISPOR in 2017-2018, and she currently is Past-Chair of the Society’s Health Science Policy Council.
Areas of expertise: Health Economics, Health Measurement, Stated Preference Research, Health Policy, and Health Services Research
Current Duke Appointments & Affiliations
Recent Scholarly Works
Economic evaluation of added neoadjuvant cemiplimab to upfront wide local excision for advanced cutaneous squamous cell carcinoma of the head and neck.
Journal article JID Innov · September 2026 Cutaneous squamous cell carcinoma occurs with increasing incidence in the aging United States population and, depending on the tumor stage, can require multimodal treatment. Neoadjuvant cemiplimab has shown promise in improving pathological response and ev ... Full text Link to item CiteFindings from the choices about abortion CaRE options (CARE) study: A discrete-choice experiment.
Journal article Contraception · July 6, 2026 OBJECTIVES: Our study aimed to quantify the extent to which individuals, when considering a hypothetical abortion at eight weeks gestation, accept tradeoffs across attributes of abortion care options. We also sought to evaluate the presence of different pr ... Full text Link to item CitePhysical rehabilitation for older patients with acute HFpEF (REHAB-HFpEF) trial: Design and rationale.
Journal article Am Heart J · July 2026 RATIONALE: Older patients hospitalized for acute decompensated heart failure with preserved ejection fraction (HFpEF) experience persistently poor outcomes, including physical disability, cognitive impairment, depression, impaired health-related quality of ... Full text Link to item CiteRecent Grants
Improving institutional processes to reduce patient harm using evidence-based standards
ResearchCo Investigator · Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development · 2025 - 2030Duke Women's Reproductive Health Research Scholars
Inst. Training Prgm or CMEMentor · Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development · 2020 - 2030Quantifying Patient Preference Information in Small-Scale Studies for Regulatory Decision Making
ResearchCo Investigator · Awarded by Food and Drug Administration · 2025 - 2028View All Grants