Overview
I am a physician-scientist with clinical and research expertise in lung transplantation and advanced lung disease, in particular idiopathic pulmonary fibrosis (IPF). My research aims to advance scientific knowledge related to the clinical and genetic risk factors underlying the development of lung fibrosis including that occurring in chronic lung transplant rejection and diseases leading to transplant, such as IPF. I also have an interest in understanding how the airway epithelial response to injury impacts lung repair, fibrosis, and tissue immunity.
Current Appointments & Affiliations
Associate Professor of Medicine
·
2023 - Present
Medicine, Pulmonary, Allergy, and Critical Care Medicine,
Medicine
Member in the Duke Clinical Research Institute
·
2012 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Reduced lung fluid club cell secretory protein informs chronic lung allograft dysfunction risk.
Journal Article Eur Respir J · April 2026 BACKGROUND: Lung transplant recipients with lower club cell secretory protein (CCSP) levels in bronchoalveolar lavage fluid (BALF) early post-transplantation are at increased risk for chronic lung allograft dysfunction (CLAD). For CLAD risk stratification, ... Full text Link to item CiteExpression of complement pathway genes is associated with progression of idiopathic pulmonary fibrosis.
Journal Article Respir Res · March 25, 2026 BACKGROUND: Studies suggest that the complement pathway may play a role in the pathogenesis of idiopathic pulmonary fibrosis (IPF). We evaluated associations between complement pathway gene expression and clinical outcomes in patients with IPF. METHODS: RN ... Full text Link to item CiteTiming of quality of life and lung function changes during the first year following lung transplantation: A multicenter prospective cohort study.
Journal Article J Heart Lung Transplant · March 2026 BACKGROUND: Lung transplantation (LT) has been shown to improve lung function and quality of life (QoL). We sought to clarify if QoL improvements coincide with improvements in spirometry assessments in the first post-transplant year. METHODS: In the multic ... Full text Link to item CiteRecent Grants
Pathological B Cells: Novel Strategies to Prevent and Treat Chronic GVHD
ResearchCo Investigator · Awarded by National Institutes of Health · 2015 - 2031Multiscale Modeling of Influenza Neutralizing Antibody and Fc Effector Biology
ResearchCo Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2029EFC17801_9085-0205 SANOFI Pro00113681
Clinical TrialPrincipal Investigator · Awarded by Sanofi US · 2024 - 2028View All Grants
Education
University of Colorado, School of Medicine ·
2005
M.D.