Overview
I am a physician-scientist with clinical and research expertise in lung transplantation and advanced lung disease, in particular idiopathic pulmonary fibrosis (IPF). My research aims to advance scientific knowledge related to the clinical and genetic risk factors underlying the development of lung fibrosis including that occurring in chronic lung transplant rejection and diseases leading to transplant, such as IPF. I also have an interest in understanding how the airway epithelial response to injury impacts lung repair, fibrosis, and tissue immunity.
Current Appointments & Affiliations
Associate Professor of Medicine
·
2023 - Present
Medicine, Pulmonary, Allergy, and Critical Care Medicine,
Medicine
Member in the Duke Clinical Research Institute
·
2012 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Trajectories of Health-Related Quality of Life in Patients With Idiopathic Pulmonary Fibrosis
Journal Article Chest Pulmonary · December 1, 2025 Background Patients with idiopathic pulmonary fibrosis (IPF) experience impairments in health-related quality of life (HRQL). Research Question What is the trajectory of decline in HRQL in patients with IPF and is this influenced by patients’ demographic/c ... Full text CiteDevelopment and validation of a bronchoalveolar lavage genomic classifier for acute cellular rejection.
Journal Article EBioMedicine · December 2025 BACKGROUND: Acute cellular rejection (ACR) is the main risk factor for chronic lung allograft dysfunction (CLAD), but diagnosis requires invasive transbronchial biopsy (TBB). We previously demonstrated the feasibility of bronchoalveolar lavage cell pellet ... Full text Link to item CiteAbnormal Spirometry One Year After Lung Transplantation May Identify Patients at Risk for Chronic Lung Allograft Dysfunction in a Multicenter Cohort
Journal Article JHLT Open · December 2025 Full text CiteRecent Grants
Multiscale Modeling of Influenza Neutralizing Antibody and Fc Effector Biology
ResearchCo Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2024 - 2029EFC17801_9085-0205 SANOFI Pro00113681
Clinical TrialPrincipal Investigator · Awarded by Sanofi US · 2024 - 2028Lung Transplant Clinical Trial Network (LT-CTN)
ResearchCo Investigator · Awarded by National Institutes of Health · 2021 - 2028View All Grants
Education, Training & Certifications
University of Colorado, School of Medicine ·
2005
M.D.