Current Appointments & Affiliations
Associate Professor of Biostatistics & Bioinformatics
·
2025 - Present
Biostatistics & Bioinformatics, Division of Integrative Genomics,
Biostatistics & Bioinformatics
Associate Professor of Computer Science
·
2025 - Present
Computer Science,
Trinity College of Arts & Sciences
Member of the Duke Cancer Institute
·
2019 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Single-cell and spatial detection of senescent cells using DeepScence.
Journal Article Cell Genom · December 10, 2025 Accurately identifying senescent cells is essential for studying their spatial and molecular features. We developed DeepScence, a method based on deep neural networks, to identify senescent cells in single-cell and spatial transcriptomics data. DeepScence ... Full text Link to item CiteKS03.4.A SPATIAL MULTI-OMIC PROFILING REVEALS DETERMINANTS OF TIL EXPANDABILITY IN HIGH-GRADE GLIOMAS
Conference Neuro-Oncology · October 3, 2025 AbstractBACKGROUNDTumor-infiltrating lymphocyte (TIL) therapy has demonstrated efficacy in melanoma and is emerging as a promising mod ... Full text CiteAdvancing biological understanding of cellular senescence with computational multiomics.
Journal Article Nat Genet · October 2025 Cellular senescence is a complex biological process that plays a pathophysiological role in aging and age-related diseases. The biological understanding of senescence at the cellular and tissue levels remains incomplete due to the lack of specific biomarke ... Full text Link to item CiteRecent Grants
Duke Program of Training in Pulmonary ReSearch to Promote, Engage and Retain Academic Researchers (PROSPER)
Inst. Training Prgm or CMEPreceptor · Awarded by National Heart, Lung, and Blood Institute · 2022 - 2026New computational methods to dynamically pinpointing the subregions carrying disease-associated rare variants
ResearchPrincipal Investigator · Awarded by National Human Genome Research Institute · 2022 - 2026Training Program in Bioinformatics at the Intersection of Cancer Immunology and Microbiome
ResearchTraining Faculty · Awarded by National Cancer Institute · 2020 - 2026View All Grants
Education, Training & Certifications
University of Pennsylvania ·
2011
Ph.D.