Current Appointments & Affiliations
Associate Professor of Biostatistics & Bioinformatics
·
2025 - Present
Biostatistics & Bioinformatics, Division of Integrative Genomics,
Biostatistics & Bioinformatics
Associate Professor of Computer Science
·
2025 - Present
Computer Science,
Trinity College of Arts & Sciences
Member of the Duke Cancer Institute
·
2019 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
B-Lightning: using bait genes for marker gene hunting in single-cell data with complex heterogeneity.
Journal Article Brief Bioinform · November 22, 2024 In single-cell studies, cells can be characterized with multiple sources of heterogeneity (SOH) such as cell type, developmental stage, cell cycle phase, activation state, and so on. In some studies, many nuisance SOH are of no interest, but may confound t ... Full text Link to item CiteMarker gene fishing for single-cell data with complex heterogeneity.
Preprint · November 6, 2024 Full text Link to item CiteSifiNet: a robust and accurate method to identify feature gene sets and annotate cells.
Journal Article Nucleic Acids Res · May 22, 2024 SifiNet is a robust and accurate computational pipeline for identifying distinct gene sets, extracting and annotating cellular subpopulations, and elucidating intrinsic relationships among these subpopulations. Uniquely, SifiNet bypasses the cell clusterin ... Full text Link to item CiteRecent Grants
Duke Program of Training in Pulmonary ReSearch to Promote, Engage and Retain Academic Researchers (PROSPER)
Inst. Training Prgm or CMEPreceptor · Awarded by National Heart, Lung, and Blood Institute · 2022 - 2026New computational methods to dynamically pinpointing the subregions carrying disease-associated rare variants
ResearchPrincipal Investigator · Awarded by National Human Genome Research Institute · 2022 - 2026Training Program in Bioinformatics at the Intersection of Cancer Immunology and Microbiome
ResearchTraining Faculty · Awarded by National Cancer Institute · 2020 - 2026View All Grants
Education, Training & Certifications
University of Pennsylvania ·
2011
Ph.D.