https://orcid.org/0000-0001-5905-6728
Research Interests
My research is focused on the development of computational and statistical methods for extracting meaningful information from the high-throughput sequencing data in cancer and/or immunology. I am interested in understanding the complicated structure and the biological background of the data, and adaptively developing new methods to utilize the data structure and biological background to increase the analysis power. Thus, my research sits at the intersection of Statistics, Machine Learning, Bioinformatics, and Genetics and Genomics/Cancer/Immunology. I enjoy collaborating with both biomedical and quantitative investigators, and involving students in those projects.
Aside from high-throughput sequencing data, I have also collaborated actively in analyzing EHR data and developing longitudinal models to compare health utilities and treatment outcomes.
Selected Grants
New computational methods to dynamically pinpointing the subregions carrying disease-associated rare variants
ResearchPrincipal Investigator · Awarded by National Human Genome Research Institute · 2022 - 2027Duke Program of Training in Pulmonary ReSearch to Promote, Engage and Retain Academic Researchers (PROSPER)
Inst. Training Prgm or CMEPreceptor · Awarded by National Heart, Lung, and Blood Institute · 2022 - 2026Training Program in Bioinformatics at the Intersection of Cancer Immunology and Microbiome
ResearchTraining Faculty · Awarded by National Cancer Institute · 2020 - 2026Race-related differential RNA splicing: novel targets for precision oncology in non-small cell lung cancer
ResearchCo Investigator · Awarded by National Institutes of Health · 2020 - 2021Bioinformatics and Computational Biology Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2005 - 2021Identification and validation of plasma-based protein biomarkers for cediranib and olaparib
ResearchCo Investigator · Awarded by Leidos Biomedical Research, Inc. · 2019 - 2020A hands-on, integrative next-generation sequencing course: design, experiment, and analysis
Inst. Training Prgm or CMETraining Faculty · Awarded by National Institutes of Health · 2016 - 2020Statistical/Computational Methods for Pharmacogenomics and Individualized Therapy
ResearchCo Investigator · Awarded by University of North Carolina - Chapel Hill · 2015 - 2020Identification and validation of plasma-based protein biomarkers for cediranib and olaparib
ResearchCo Investigator · Awarded by Leidos Biomedical Research, Inc. · 2019 - 2019Duke CTSA (UL1)
ResearchBiostatistician Investigator · Awarded by National Institutes of Health · 2013 - 2018External Relationships
- Florida International University
This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.