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Yuan Wu

Associate Professor in Biostatistics & Bioinformatics
Biostatistics & Bioinformatics, Division of Biostatistics
Duke Box 2721, Durham, NC 27710
2424 Erwin Road, 11101 Hock Plaza Suite 1102, Durham, NC 27710

Overview


Survival analysis, Sequential clinical trial design, Machine learning, Causal inference, Non/Semi-parametric method, Statistical computing

Current Appointments & Affiliations


Associate Professor in Biostatistics & Bioinformatics · 2022 - Present Biostatistics & Bioinformatics, Division of Biostatistics, Biostatistics & Bioinformatics
Member of the Duke Cancer Institute · 2021 - Present Duke Cancer Institute, Institutes and Centers

Recent Publications


Win Ratio as an Effect Size Measure Under Non-Proportional Hazards: A Comparison With Difference in Restricted Mean Survival.

Journal Article Stat Med · May 2026 When the proportional hazards assumption does not hold, the hazard ratio can misrepresent treatment effects in survival analysis. We evaluate the win ratio, originally proposed for prioritizing multiple outcomes, as an effect size measure for a single surv ... Full text Link to item Cite

Sequential design for paired ordinal categorical outcome.

Journal Article Stat Methods Med Res · June 2025 This study addresses a critical gap in the design of clinical trials that use grouped sequential designs for one-sample or paired ordinal categorical outcomes. Single-arm experiments, such as those using the modified Rankin Scale in stroke trials, undersco ... Full text Link to item Cite

Intensifying Salvage Therapy in Prostate-specific Antigen Recurrent Prostate Cancer After Radical Prostatectomy with Apalutamide, Salvage Radiation, and Docetaxel: The Phase 2 STARTAR Trial.

Journal Article Eur Urol Oncol · April 2025 BACKGROUND AND OBJECTIVE: Androgen deprivation therapy (ADT) with salvage radiation therapy (RT) improves survival for patients with prostate-specific antigen (PSA) recurrence after radical prostatectomy (RP) for prostate cancer (PC), but many patients suf ... Full text Link to item Cite
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Recent Grants


Assessment of the Optimal Settings of TFL for Laser Lithotripsy and Associated Thermal Injury Risk

ResearchCo Investigator · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2025 - 2028

Kidney Cancer Research Program Clinical Consortium Duke University Clinical Trial Site Award

ResearchBiostatistician · Awarded by Department of Defense · 2024 - 2028

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Education


University of Iowa · 2010 Ph.D.