Overview
Manesh Patel is the Chief of the Division of Cardiology and the Division of Clinical Pharmacology. His clinical interests include diagnostic and interventional coronary angiography, peripheral angiography and endovascular intervention. His is involved in several clinical trials involving patients with cardiovascular disease and in cardiac imaging. He is also the Chair of the American College of Cardiology Task Force for Appropriate Use Criteria for Cardiovascular Procedures and is Chair of the American Heart Association Diagnostic and Interventional Cath Committee.
Patel's interest in cardiac imaging, quality of care, cardiac devices is also evident in his research. His integration of these efforts into his roles at Duke was recognized in 2010 when he received the prestigious Duke Cardiology Fellowship Mentor Award. In 2011, Dr. Patel was named the endowed John Bush Simpson Assistant Professor of Cardiology. In 2013, Dr. Patel received the Robert M. Califf Faculty clinical research Award.
Currently, Dr. Patel is leading an effort to redesign the delivery of care to patients undergoing invasive catheterization procedures in the health system with a specific aim of measure and providing individualized, patient centered, innovative, and efficient care.
Patel's interest in cardiac imaging, quality of care, cardiac devices is also evident in his research. His integration of these efforts into his roles at Duke was recognized in 2010 when he received the prestigious Duke Cardiology Fellowship Mentor Award. In 2011, Dr. Patel was named the endowed John Bush Simpson Assistant Professor of Cardiology. In 2013, Dr. Patel received the Robert M. Califf Faculty clinical research Award.
Currently, Dr. Patel is leading an effort to redesign the delivery of care to patients undergoing invasive catheterization procedures in the health system with a specific aim of measure and providing individualized, patient centered, innovative, and efficient care.
Current Appointments & Affiliations
Richard Sean Stack, M.D. Distinguished Professor
·
2020 - Present
Medicine, Cardiology,
Medicine
Professor of Medicine
·
2017 - Present
Medicine, Cardiology,
Medicine
Chief, Division of Clinical Pharmacology
·
2016 - Present
Medicine, Cardiology,
Medicine
Chief, Division of Cardiology
·
2016 - Present
Medicine, Cardiology,
Medicine
Member in the Duke Clinical Research Institute
·
2006 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
IVUS, OCT, or Angiography as Guidance for PCI in Complex Coronary Artery Lesions
Journal Article Jacc Cardiovascular Interventions · January 12, 2026 Background Intravascular imaging–guided percutaneous coronary intervention (PCI) reduces cardiovascular events compared with angiography-guided PCI alone. However, there is a paucity of data comparing these approaches in patients with complex coronary arte ... Full text CiteLong-term prognostic impact of complete revascularisation defined by CT-derived fractional flow reserve.
Journal Article Heart · December 3, 2025 BACKGROUND: Complete revascularisation has been associated with improved short-term outcomes in patients with coronary artery disease, but whether these benefits persist long-term and can be defined non-invasively remains uncertain. We investigated the lon ... Full text Link to item CitePatient-directed data capture for clinical research: A pilot study testing two platforms.
Journal Article Contemp Clin Trials · December 2025 BACKGROUND: Patient-directed data capture enables individuals to access and share their electronic health record (EHR) data, potentially supporting patient engagement while also reducing data fragmentation. Although many vendors offer patient-directed data ... Full text Link to item CiteRecent Grants
1/2 IMPRoving Outcomes in Vascular DisEase - Aortic Dissection (IMPROVE-AD)
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 20301/2 Low dose colchicine in pAtients with peripheral artery DiseasE to assess residual vascular risk (LEADER-PAD)
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2025 - 2029Splanchnic Nerve Modulation In Heart Failure (Splanchnic X)
ResearchCollaborator · Awarded by National Heart, Lung, and Blood Institute · 2024 - 2029View All Grants
Education, Training & Certifications
Emory University ·
1997
M.D.