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Manesh Raman Patel

Richard Sean Stack, M.D. Distinguished Professor
Medicine, Cardiology
DUMC 3330, Durham, NC 27710
2301 Erwin Road, HAFS Building, Room 8695, Durham, NC 27710

Overview


Manesh Patel is the Chief of the Division of Cardiology and the Division of Clinical Pharmacology.  His clinical interests include diagnostic and interventional coronary angiography, peripheral angiography and endovascular intervention.  His is involved in several clinical trials involving patients with cardiovascular disease and in cardiac imaging.  He is also the Chair of the American College of Cardiology Task Force for Appropriate Use Criteria for Cardiovascular Procedures and is Chair of the American Heart Association Diagnostic and Interventional Cath Committee.

Patel's interest in cardiac imaging, quality of care, cardiac devices is also evident in his research.  His integration of these efforts into his roles at Duke was recognized in 2010 when he received the prestigious Duke Cardiology Fellowship Mentor Award.   In 2011, Dr. Patel was named the endowed John Bush Simpson Assistant Professor of Cardiology.  In 2013, Dr. Patel received the Robert M. Califf Faculty clinical research Award.

Currently, Dr. Patel is leading an effort to redesign the delivery of care to patients undergoing invasive catheterization procedures in the health system with a specific aim of measure and providing individualized, patient centered, innovative, and efficient care.

Current Duke Appointments & Affiliations


Richard Sean Stack, M.D. Distinguished Professor · 2020 - Present Medicine, Cardiology, Medicine
Professor of Medicine · 2017 - Present Medicine, Cardiology, Medicine
Chief, Division of Clinical Pharmacology · 2016 - Present Medicine, Cardiology, Medicine
Chief, Division of Cardiology · 2016 - Present Medicine, Cardiology, Medicine
Member in the Duke Clinical Research Institute · 2006 - Present Duke Clinical Research Institute, Institutes and Centers

Recent News Items


Published July 6, 2026
Duke Heart Specialists Lead American Heart Association
Published February 7, 2024
Gift to Support Heart Transplant Patients and Their Families
Published April 15, 2022
School of Medicine Celebrates 2022 Faculty Achievement Awards

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Recent Scholarly Works


Predictors of ischemic stroke and major bleeding among patients with atrial fibrillation in clinical practice.

Journal article Am Heart J · October 2026 BACKGROUND: Numerous risk scores exist to quantify the risk of ischemic stroke risk in patients with atrial fibrillation or flutter (AF/AFL). However, how these tools perform in cohorts or those already on oral anticoagulation (OAC) therapy is unclear. MET ... Full text Link to item Cite

Secondary prevention strategies for patients with lower extremity peripheral artery disease after successful peripheral vascular intervention.

Journal article Am Heart J · September 2026 BACKGROUND: Individuals with lower extremity peripheral artery disease (LE PAD) represent a subset of patients with atherosclerotic cardiovascular disease that are among the highest risk for major adverse cardiovascular and limb events. Despite this, LE PA ... Full text Link to item Cite

Design and Rationale of the pERSonalized cardIovascuLar dIsease prEvention, treatmeNt, and CarE (RESILIENCE) study.

Journal article Contemp Clin Trials · August 2026 BACKGROUND: Obesity is a growing epidemic associated with cardiovascular disease (CVD). The RESILIENCE study aimed to understand the factors underlying heterogeneity in CVD development among individuals with obesity as well as the variability in response t ... Full text Link to item Cite
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Recent Grants


1/2 IMPRoving Outcomes in Vascular DisEase - Aortic Dissection (IMPROVE-AD)

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2030

1/2 Low dose colchicine in pAtients with peripheral artery DiseasE to assess residual vascular risk (LEADER-PAD)

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2025 - 2029

Splanchnic Nerve Modulation In Heart Failure (Splanchnic X)

ResearchCollaborator · Awarded by National Heart, Lung, and Blood Institute · 2024 - 2029

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Education


Emory University · 1997 M.D.