Overview
Dr. Smith completed his residency in pediatrics and a fellowship in neonatal medicine at Duke University Medical Center in 2004 and 2007, respectively. He completed an MHS in clinical research from Duke University in 2006 and an MPH in biostatistics from the University of North Carolina at Chapel Hill in 2009. His research is focused on pediatric drug safety, neonatal pharmacology, and the epidemiology of neonatal infections. Dr. Smith is or has been the protocol chair for more than 14 studies of drugs in infants and children. He is the Principal Investigator for the Environmental Influences on Child Health Outcomes (ECHO) Coordinating Center.
Current Appointments & Affiliations
Samuel L. Katz Distinguished Professor of Pediatrics
·
2018 - Present
Pediatrics, Neonatology,
Pediatrics
Professor of Pediatrics
·
2015 - Present
Pediatrics, Neonatology,
Pediatrics
Member in the Duke Clinical Research Institute
·
2007 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Outcomes of Mothers and Infants Affected by COVID-19.
Journal Article Am J Perinatol · January 2026 The long-term effects of the novel coronavirus disease 2019 (COVID-19) infection during pregnancy are poorly characterized in mothers and their infants. The aim of this study was to assess the physical, mental, and emotional well-being of mothers and infan ... Full text Link to item CiteA comparison of institutional review board models and study efficiency in the Environmental influences on Child Health Outcomes Cohort Consortium.
Journal Article Contemp Clin Trials · January 2026 BACKGROUND: Institutional review board (IRB) approval is a key step in site activation and study initiation. Single IRBs aim to improve the timeliness of IRB review through centralization and standardization, whereas local IRBs conduct reviews only for spe ... Full text Link to item CiteEarly Effective Antibiotic Therapy and Meningitis following a Bloodstream Infection in Hospitalized Infants: A Cohort Study.
Journal Article Am J Perinatol · December 2025 This study aimed to evaluate the role of early effective antibiotic therapy in preventing secondary meningitis as a sequelae of bacterial bloodstream infections (BSI).In this multicenter cohort study, we identified blood cultures that were positive for Gro ... Full text Link to item CiteRecent Grants
Comparative Effectiveness of Emerging Medications in Children with Inflammatory Bowel Disease
ResearchCo Investigator · Awarded by University of North Carolina - Chapel Hill · 2025 - 2031iPediHeart: Interdisciplinary Research Training Program for Pediatric Heart Disease
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2025 - 20302/3 CTSA K12 Program at Duke University
ResearchMentor · Awarded by National Institutes of Health · 2025 - 2030View All Grants
Education, Training & Certifications
University of North Carolina, Chapel Hill ·
2009
M.P.H.
Duke University, School of Medicine ·
2006
M.H.S.
Mercer University ·
2001
M.D.